Polychelates of Trivalent Selected Metal Ions of ‘4f’ Block With Phenolic Resin and Their Antimicrobial Activities

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DOI: 10.21522/TIJAR.2014.03.01.Art039

Authors : Nileshkumar M Baria, Sanyogita Sharma, Rakshit Ameta, Patel Vasant M, Joshi J. D.

Abstract:

The polymeric ligand (resin) was prepared from 2,4-dihydroxy benzophenone with 1,4-butane diol in presence of polyphosphoric acid as a catalyst at   160° C for 13 hrs.. The poly [(2,4-dihydroxy benzophenone) 1,4-butylene ] i.e. H(DHBP-1,4-BD) forms, 1:2 metal: ligand chelates with La(III), Pr(III), Nd(III), Sm(III),Gd(III), Tb(III), and Dy(III). The polymeric ligand and its polychelates were characterized on the basis of elemental analyses, electronic spectra, magnetic susceptibilities, thermogravimetric analysis, NMR and IR results. The molecular weight was determined using number average molecular weight ( ) by the vapour pressure osmometry (VPO) method. All the polychelates are paramagnetic in nature except La(III). The resin and their polychelates were tested for antimicrobial activity against E. coli, B. substilis, and S. aureus (bacteria) and S. cerevisiae (yeast). It is found that the synthesized polychelates can be used as an effective and efficient antibacterial agents.

References:

[1.] Arimoto F.S., HavenA.C., Derivatives of dicyclopentadienyliron, J. Am. Chem. Soc., 77, 6295-6397, 1955.

[2.] Joshi J.D., Patel N.B., Patel S.D., Ion-exchange study of poly [(2,4-dihydroxy benzophenone)propylene]resin and its polychelates: Synthesis, characterization. J. Macro. Molecular Sci. Part A, PAC., 43, 1179-1188, 2006.

[3.] Mizuta T., Onishi M., Miyoshi K., Photolytic ringopening polymerization of phosphorus–birdge. 1: Ferrocenophane coordinating to an organometallic fragment, Organometallics, 19, 5005-5009, 2000.

[4.] Rivas B L., Maturana H.A., Molina M.J., Gomej- Anton M.R., Rosa M., Pierola I.F., Metal ion binding properties of poly (N-vinylimidazole) hydrogels, J. Appl. Polym. Sci., 67, 1109, 1998.

[5.] Tusa H., Paavola A., Harjula R., Letho J., 8th Int. Conf. of Radioactive Waste Management and Environmental Remediation, 3, 42, 2001.

[6.] Orazzhanova L.K., Yashkarova M.G., Bimendina L.A., Kudaibergenov S.E., Binary and ternary polymerstrontium complexes and the capture of radioactive strontium-90 from the polluted soil of the Semipalatinsk Nuclear Test site, J. Appl. Polym. Sci., 87, 759-769, 2003.

[7.] Atia A.A., Donia A.M., Elwakeel K.Z., Selective separation of mercury (II) useing a synthetic resin containing amine and mercaptan as chelating groups, Reacti. Funct. Polymer, 65, 267-276, 2005.

[8.] Jacob A.M., Yizhak M., Ion-Exchange and Solvent Extraction, 13th Ed., Marcel & Dekker Inc., New York, 1997.

[9.] Geckeler K.E., Rongnong Z., Reaction products of amino or amide group containing polymer with compounds containing functional and linking groups, Ger. Offen. DE , 4227019, 1994; Chem. Abstr., 121, 10302f, 1994.

[10.] Alelah A., Moet A., Functionalised Polymers and Applications; Chapman and Hall, London, 93, 1990.

[11.] Vankrevelen D.W, New developments in the field of flame-resistance fibers, Angew. Makromol. Chem., 22, 132, 1972.

[12.] Dentini M., Santis P., Vardin A., Formation properties and structures of bis(O-hydroxybenzylideneamine) copper(II) chelates of polypeptide ligands, Macromol. Chem., 175, 327, 1974.

[13.] Patel M.N., Patel J.B., Chelateing polymers of phenolic resin, J. Macromol. Sci. A Chem., 19, 193-199, 1983.

[14.] Nho Y.C., Park J.S., Jin J.H., Antibacterial activity of sulfonated styrene-grafted polypropylene fabric and its metallic salt, J. Macro. Molecular Sci. Part A, PAC, 36, 731 -740, 1993.

[15.] Jayakumar R., Rajkumar M., Nagendran R., Nanjundan S., Synthesis and characterization of metal-containing polyurethanes with antimicrobial activity, J. Appl. Polym. Sci., 85, 1194 - 1206, 2002.

[16.] Belfiore L.A., Curdie M.P. M., Das P.K., Macromolecule-metal complexes: Ligand field stabilization and thermophysical property modification. Polymer, 42, 9995 - 10006, 2001

[17.] Nursen S., Ebru K., Bekir S., Aulin O., Synthesis of some polymer-metal complexes and elucidation of their structures, J. Macro. Molecular Sci. Part A, PAC, 43, 1227-1235, 2006.

[18.] Silverstein R.M., Webster, F.X., Spectrometric Identification of Organic Compounds, 6th Ed., John Wiley, New York, 1998.

[19.] Eliassi A., Modarress H., Water activities in binary and ternary aqueous system of poly(ethylene glycol), poly(propylene glycol) and dextran, Euro. Polym. J., 37, 1487-1492, 2001.

[20.] Nikolaev V.A., Logvinenko L.T., Myachina L.T., Thermal Analysis, Academic; press New York., 779, 1969.

[21.] Kriza A., Reiss A., Florea S., Carproin T., Studies on complexes of cobalt(II), nickel(II), copper(II), zinc(II) and cadmium(II) with Schiff base derived from 3-aminodibenzofuran and salicylaldehyde, J. Ind. Chem. Soc., 77, 207-208, 2000.

[22.] Stanier R.Y., Introduction to the Microbial World, 5th Ed., Prentice Hall, N.J., 16-20, 1986.

[23.] Chohan Z. H., Kausar S., Synthesis, characterization and biological properties of tridentate NNO, NNS, and NNN donor thiazole derived furnyl, thiophenyl and pyrollyl Schiff bases and their cobalt(II), copper( II), nickel(II) and zinc(II) metal chelates, Met.- Based Drugs, 7, 17-22, 2000.