Abstract:

Objective: This paper evaluates HIV sero-positivity among Multi- Drug Resistance Tuberculosis adult patients at Ndola Central Hospital, Ndola, Zambia.

Research question: How many patients who were admitted at Ndola Central Hospital had HIV / MDR- TB co-infections, and how many died?

Method: A Retrospective Cohort study using the existing data and laboratory results in patient files and MDR TB register (sampling frame) were reviewed for all MDR TB patients whose culture and drug susceptibility test done at Ndola Central Hospital were assessed for HIV sero-status from January 2010 to June 2014. Review of records was done from 15/08//2014 to 22//o8/14 and sample comprised of 114 records which were available during the stated period using convenient sampling. A semi-structured questionnaire was used for data collection on the existing data base on patient’s file and MDR- TB patient register. Data analyzed using Epi data version 3 and bivariate analysis.

Results: The study revealed that 68.1% of the MDR TB patients were males, compared to 31.9% females; however there was no association between MDR TB and sex. The study showed that 42% of the respondents with MDR TB were co-infected with HIV. It also revealed that mortality among HIV / MDR TB co-infected patients was 36% and those negative accounted 12.7% showing an association between HIV sero status and MDR TB co-infection mortality.

Conclusion: HIV / MDR TB co-infection is a major public health problem needing urgent interventions, and proper treatment options for policy direction.

Keywords: Evaluation, HIV / MDR-TB co-infection, Ndola, Zambia.

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[28]. DOI: http://dx.doi.org/10.1016/j.tube.2013.08.009 Home » Citations » Journal of AIDS & clinical research » Risk of Death among HIV Co-Infected Multidrug Resistant Tuberculosis Patients, Compared To Mortality in the General Population of South Africa.