Meta-Analysis: A Key Statistical Method in Clinical Research Through A Review of Preterm Birth and Childhood Wheezing Disorders

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Authors : Pradnya Mahatme


Meta-analysis is a statistical approach to combine the data derived from a systematic-review. Therefore, every meta-analysis should be based on an underlying systematic review, but not every systematic review leads to a meta-analysis. Meta-analysis offers a rational and helpful way of dealing with a number of practical difficulties that beset anyone trying to make sense of effectiveness research.

This article review was written after details and critical assessment of the research conducted by Been JV The researchers undertook meta-analysis and a systematic review investigating risks of asthma/wheezing disorders in children born preterm, including the increasing numbers who, as a result of advances in neonatal care, now survive very preterm birth. The trigger of research was accumulating evidence which implicates early life factors in the aetiology of non-communicable diseases, including asthma/wheezing disorders.

It was evident that preterm birth particularly very preterm birth increases the risk of asthma. Been JV concluded that these is greater need to focus on understanding mechanisms and translate it into preventive actions.


Meta-analysis, Systemic Review, Preterm Birth, Asthma, Wheezing, Disorders


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