Current status and potential of South African hospitals to implement research to overcome health challenges, archive international health goals and increase capacity of clinicians and nurses.

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Authors : Seahloli M S, Kannan S, Demana P


South Africa has a significant burden of both communicable and non-communicable diseases are on the rise. Clinical research has been portrayed by Ministry of health in South Africa to improve the health condition of the nation reducing the disease burden. However, the research has not kicked in as planned by the research output and awareness of public regarding the clinical research. Hence, the present study was conducted to assess the hurdles faced by the health care personnel in implementing research in their institutions in South Africa .

Keywords: Clinical Research, South African hospitals. Clinician’s capacity, naïve patients.


[1]. Manyosi BM, Lawn JE, van Niekerk A, Bradshaw D, Karim SSA and Coovadia HM; 2012, Health in South Africa: changes and challenges since 2009; The Lancet, Online Nov http;//

[2]. Department of Health. Progress report Dec 2011. and (accessed 3 Aug 2015)

[3]. Department of Health. Malaria Elimination Monitoring and Evaluation Plan 2012–2018. Pretoria: Department of Health, 2012.

[4]. Coovadia H and Coovadia I. Science and society: the HIV epidemic and South African political responses. In: Finn A, Pollard AJ, eds. 2008; Hot topics in infection and immunity in children IV. New York, Springer, : pp 16−28.

[5]. Makgoba MW. 2000; HIV/AIDS: the peril of pseudoscience. Science, 288: pp 1171.

[6]. The Lancet. 2012; South Africa’s AIDS response: the next 5 years. Lancet; 379: pp 1365.

[7]. South African Government. Outline of the national HIV Counselling and Testing (HCT) campaign by Dr Aaron Motsoaledi, Minister of Health. March 25, 2010. (accessed 3 Aug 2015).

[8]. Bradshaw D, Dorrington RE and Laubscher R. 2012; Rapid mortality surveillance report 2011. Cape Town: South African Medical Research Council, 2012.

[9]. National Health Laboratory Service. Xpert MTB/RIF report June 2013. (accessed 3 Aug 2016).

[10]. Department of Health. National Health Insurance in South Africa: policy paper. Aug 12, 2011. national-health-act-no-61-of-2003-policy-on-national-health-insurancedraft_20110812-GGN-34523-00657 (3 Aug 2015).

[11]. South Africa Annual report WHO 2009. (accessed 3 Aug 2015).

[12]. Nachega JB, Uthman OA, Ho YS, Lo M, Anude C, Kayembe P et al. 2012; Current status and future prospects of epidemiology and public health training and research in the WHO African region. Int J of Epidemiology; vol 41: pp 1829–1846. doi:10.1093/ije/dys189

[13]. Mayosi BM, Flisher AJ, Lalloo UG et al. 2009; Health in South Africa 4. The burden of non-communicable diseases in South Africa. Lancet, vol 374: pp 934–47.

[14]. Tollman SM, Kahn K, Sartorius B et al. 2008; Implications of mortality transition for primary health care in rural South Africa: a population-based surveillance study. Lancet, Vol 372: pp 893–901.

[15]. Groenewald P, Bradshaw D, Daniels J et al. 2008; Cause of Death and Premature Mortality in Cape Town, 2001–2006. Cape Town: South African Medical Research Council.

[16]. Mayosi BM, Dhai A, Folb P, et al. 2009; Consensus report on revitalising clinical research: a study on clinical research and related training in South Africa. Pretoria: Academy of Science of South Africa.

[17]. Ekeroma A, Kenealy T and Hill AG; 2015, Educational and Wider Interventions that Increase Research Activity and Capacity of Clinicians in Low to Middle Income Countries: A Systematic Review and Narrative Synthesis. J Res Development; vol 3, issue 120: pp 1-9 doi: 10.4172/jrd.1000120

[18]. Kahn M. 2011; A bibliometric analysis of South Africa’s scientific outputs – some trends and implications. S Afr J Sci,107 (1/2), Art No 406: pp1-6. DOI:10.4102/sajs.v107i1/2.406

[19]. Sanders D and Haines A. 2006; Implementation research is needed to achieve international health goals. PLoS Med 3(6): e186. DOI: 10.1371/journal.pmed.0030186

[20]. McKee M, Stuckler D and Basu S. 2012; Where There Is No Health Research: What Can Be Done to Fill the Global Gaps in Health Research? PLoS Med 9(4): e1001209. doi:10.1371/journal.pmed.1001209

[21]. Hanney SR and Gonzalez-Block MA. 2013; Organizing health research systems as a key to improving health: the World Health Report 2013 and how to make further progress. Health Research Policy and Systems.

[22]. National Planning Commission. National Development plan, Chapter 10, 2015 (accessed 5 Aug 2015)

[23]. Statistics South Africa. Mid-year population estimates, 2011. (accessed 5 Aug 2015 2012).

[24]. Day C, Gray A, Budgell E. Health and related indicators: South African health review 2011. Durban: Health Systems Trust, 2012.

[25]. Statistics South Africa. Living conditions of households in SA 2008/2009. Pretoria: Statistics South Africa, 2011.