Tackling the Problem of Mpox: A Global Phenomenon
Abstract:
This article, Tackling the Problem of Mpox: A Global Phenomenon, examines the resurgence and global impact of Mpox. Mpox, previously known as Monkeypox, has rapidly evolved from a localized health issue in Central and West Africa into a global public health challenge. The 2022 outbreak, which spread across several continents, revealed just how easily infectious diseases can cross borders in our interconnected world and how vital global cooperation has become. This conceptual article explores the patterns of Mpox transmission, its social and economic impacts, and how different countries have responded to the outbreak. It also sheds light on key challenges such as weak disease surveillance and unequal access to vaccines. Using global health frameworks and the One Health approach, this paper recommends practical strategies such as stronger surveillance systems, fair vaccine distribution, cross-border collaboration, and continuous health education. In the end, it emphasizes that tackling Mpox is not just a medical or policy issue; it’s a shared responsibility that calls for global solidarity, compassion, and commitment to building a healthier, more prepared world.
References:
[1]. Adejoro,
L., 2022, Nigeria's monkeypox death toll highest in Africa-WHO. Punch.
Available
from:https://punchng.com/nigerias-monkeypox-death-toll-highest-in-africa-who/
[2]. Ahmed,
S. K., Mohamed, M. G., Dabou, E. A., 2023, Monkeypox (mpox) in immunosuppressed
patients.F1000Res;12:127.Published 2023 Feb 2.
[3]. Alexander,
C. A. A., & Wang, L. 2023, Monkeypox: Re-emerging Infectious Disease and
One Health Strategy. Preprints. https://doi.org/10.20944/preprints202305.0376.v1
[4]. American
Society for Microbiology. Mpox. 2023, Available from :
https://asm.org/resource-pages/monkeypox
[5]. Belay,
E. D., Kile, J. C., Hall, A. J., Barton-Behravesh, C., Parsons, M. B., Salyer,
S., & Walke, H., 2017, Zoonotic Disease Programs for Enhancing Global
Health Security. Emerging infectious diseases, 23(13),
S65–S70. https://doi.org/10.3201/eid2313.170544
[6]. Bhattacharya,
M., Dhama, K., & Chakraborty, C., 2022, Recently spreading human monkeypox
virus infection and its transmission during COVID-19 pandemic period: A
travelers' prospective. Travel medicine and infectious disease, 49,
102398. https://doi.org/10.1016/j.tmaid.2022.102398
[7]. Bosworth, A., Wakerley, D., Houlihan, C. F.,
& Atabani, S. F., 2022, Monkeypox: An old foe, with new challenges. Infection
prevention in practice, 4(3), 100229. https://doi.org/10.1016/j.infpip.2022.100229
[8]. Branda,
F., Romano, C., Ciccozzi, M., Giovanetti, M., Scarpa, F., Ciccozzi, A., &
Maruotti, A., 2024, Mpox: An Overview of Pathogenesis, Diagnosis, and Public
Health Implications. Journal of clinical medicine, 13(8),
2234. https://doi.org/10.3390/jcm13082234
[9]. CDC,
2024; Mpox Outbreaks Among Gay, Bisexual, and Other Men Who Have Sex with Men
in the United States 2024. https://www.cdc.gov/forecast-outbreak-analytics/about/modeling-forecasting/mpox-gbmsm-technical-brief.html
[10]. Centers
for Disease Control and Prevention (CDC). 2023, Technical Report 4:
Multi-National Mpox Outbreak, United States, 2022. Available from:
https://www.cdc.gov/poxvirus/Mpox/cases-data/technical-report/report-4.html
[11]. Centers
for Disease Control and Prevention (CDC). 2024, Mpox in Animals and Pets.
Available from:
https://www.cdc.gov/poxvirus/mpox/veterinarian/mpox-in-animals.html
[12]. Centers
for Disease Control and Prevention (CDC). 2025, About Mpox. Available from:
https://www.cdc.gov/poxvirus/mpox/if-sick/treatment.html
[13]. Cleveland
Clinic. 2023, Mpox. Cleveland Clinic Health Library. Available from:
https://my.clevelandclinic.org/health/diseases/22371-monkeypox
[14]. Dananberg, A., Striepen, J., Rozowsky, J. S.,
& Petljak, M., 2024. APOBEC
Mutagenesis in Cancer Development and Susceptibility. Cancers, 16(2),
374. https://doi.org/10.3390/cancers16020374
[15]. Erkyihun,
G., & Bekele, M., 2022, One Health Approach for the Control of Zoonotic
Diseases. Zoonoses. 2. 10.15212/ZOONOSES-2022-0037.
[16]. Guzzetta,
G., Marziano, V., Mammone, A., Siddu, A., Ferraro, F., Caraglia, A., Maraglino,
F., et al., 2024, The decline of the 2022 Italian mpox epidemic: Role of
behavior changes and control strategies.
[17]. Haverkate,
M. R., Willemstein, I. J., van Ewijk, C. E., Adam, P. C., Lanooij, S. J.,
Jonker-Jorna, P., et al., 2024, Factors potentially contributing to the decline
of the mpox outbreak in the Netherlands, 2022 and 2023. Euro surveillance : bulletin Europeen sur les maladies transmissibles =
European communicable disease bulletin, 29(21), 2300608. https://doi.org/10.2807/1560-7917.ES.2024.29.21.2300608
[18]. Health
Direct, 2023, Monkeypox, Available from:
https://www.healthdirect.gov.au/monkeypox
[19]. Husein,
S. A., Hussein, J. A., Alleyo, T. G., Jilo, S. A., 2023, A Review on Monkey
Pox: Role of One Health Approach Against Monkey Pox.
[20]. Jennifer,
H. M., Braden, C. R., Bowen, M. D., McCollum, A. M., McDonald, R., Carnes, N.,
Carter RJ, Christie A.
[21]. Keesing,
F., et al., 2010, Impacts of biodiversity on the emergence and transmission of
infectious diseases.
[22]. Krug,
C., Tarantola, A., Chazelle, E., et al., 2023, Mpox outbreak in France:
epidemiological characteristics and sexual behaviour of cases aged 15 years or
older, 2022.
[23]. Natami,
M., Gorgzadeh, A., Gholipour, A., Fatemi, S. N., Firouzeh, N., Zokaei, M.,
Kalavi, S., 2024, An overview on mRNA-based vaccines to prevent monkeypox
infection.
[24]. Luong Nguyen, L. B., Ghosn, J., Durier, C.,
Tachot, C., Tartour, E., Touati, A., Simon, T., et al., 2022. A prospective national cohort evaluating ring
MVA vaccination as post-exposure prophylaxis for monkeypox. Nature
medicine, 28(10), 1983–1984. https://doi.org/10.1038/d41591-022-00077-1
[25]. Phillips, G., 2nd, Curtis, M. G., Felt, D.,
Davoudpour, S., Rodriguez-Ortiz, A. E., et al., 2024. Changes
in Sexual Behaviors Due to Mpox: A Cross-Sectional Study of Sexual and Gender
Minority Individuals in Illinois. Prevention science: the official
journal of the Society for Prevention Research, 25(4), 628–637.
https://doi.org/10.1007/s11121-023-01604-3
[26]. Roper,
R. L., Garzino-Demo, A., Del Rio, C., et al., 2023, Monkeypox (Mpox) requires
continued surveillance, vaccines, therapeutics, and mitigating strategies.
[27]. Ramchandani,
M. S., Berzkalns, A., Cannon, C. A., et al. 2023, Effectiveness of the modified
vaccinia ankara vaccine against MPX in men who have sex with men: a
retrospective cohort analysis, Seattle, Washington.
[28]. Samolej,
J., White, I. J., Strang, B. L., Mercer, J., 2024, Cardiac glycosides inhibit
early and late vaccinia virus protein expression.
[29]. Shchelkunova,
G. A., Shchelkunov, S. N. N., 2022, Smallpox, Monkeypox, and Other Human
Orthopoxvirus Infections.
[30]. Shen,
M, Lai, H., Zhang, L., 2023, Targeted interventions for individuals at high
risk are essential for MPX control.
[31]. Tajudeen,
Y. A., et al., 2023, Monkeypox: A review of a zoonotic disease of global public
health concern.
[32]. The
Microbe. 2024, Unveiling the Global Surge of Mpox (Monkeypox): A comprehensive
review of current evidence. Volume 4. Available from:
https://www.sciencedirect.com/science/article/pii/S2950194624001080#bib147
[33]. Traore,
T., Shanks, S., et al., 2023, How prepared is the world? Identifying weaknesses
in existing assessment frameworks for global health security through a One
Health approach.
[34]. WHO.
2024, Mpox overview. Available from:
https://www.who.int/news-roomn/fact-sheets/detail/mpox?utm source=chatgpt.com
[35]. WHO/FAO/OIE,
2004, Report of the WHO/FAO/OIE joint consultation on emerging zoonotic
diseases; in collaboration with the Health Council of the Netherlands.
[36]. WOAH.
2022, One Health. Available from:
https://www.woah.org/en/what-we-do/global-initiatives/one-health/
[37]. World
Health Organization (WHO). 2024, Multi-country outbreak of mpox. Available
from:
https://www.who.int/docs/default-source/coronaviruse/situation-reports/20240531mpoxexternal-sitrep33.pdf?sfvrsn=74858ef73&download=true
[38]. World
Health Organization (WHO). 2022, Interim guidance. Available from:
https://www.who.int/publications/i/item/WHO-MPX-laboratory-2022.1
[39]. World
Health Organization (WHO). 2023, Diagnostic testing for the monkeypox virus
(MPXV). Available from:
https://www.who.int/publications/i/item/who-mpx-laboratory-2023-1
[40]. Zardi,
E. M., Chello, C., 2022, Human Monkeypox-A Global Public Health Emergency.
[41]. Zhou, Y., Chen, Z., 2023, Mpox: a review of laboratory detection techniques.
