The biggest burden in peritoneal
dialysis is still peritonitis which increases the rate of mortality and hospitalization.
The aim of our research was to address one of the ISPD (international society of
peritoneal dialysis) guidelines 2016 which advocate the use of prophylactic antibiotic
in peritoneal dialysis patients before going to colonoscopy, but this recommendation
is class C which means a weak one. Our aim was to look at the effect of giving intraperitoneal
ceftazidime before the procedure of colonoscopy in reducing the possible risk of
Patients and methods: Over
a period of 2 years and 6 months, from January 2016 we managed to enroll 120 patients
out of 163 whom we performed 120 colonscopies. Patients were randomized for Ceftazidime
use by 1:1 method, ending up with 60 patients in group A who received the drug and
60 patients in group B who did not receive the drug.
Results: peritonitis occurred
within 48 hours following the procedure. It was documented in 4 (6.7%) and 5 (8.3%)
patients in groups 1 and 2 respectively (p
=0.3243); the causative organisms were mainly gram-negative bacteria.
Conclusion: It appeared that
giving intraperitoneal Ceftazidime prior to colonoscopy did not offer greater benefits
in reducing the risk of peritonitis when compared with the group who did not receive
dialysis, peritonitis, colonoscopy, ESRD, colon cancer, ceftazidime.
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