Abstract:

Diabetes mellitus (DM) is a disease caused by a deficiency or diminished effectiveness of endogenous insulin. The complicationsof diabetes mellitus are known to be very severe, unbearable, incapacitating, fatal, and has high health and economic burdens. This study was conducted to compare hematological parameters in diabetic males and females compared with non-diabetic individuals. This study was done at the Defense Reference Laboratory, Asokoro, Abuja, Nigeria. Venipuncture was performed on all participants; Complete Blood Count was carried out with 2ML-EDTA blood tubes using the Sysmex platform while Fasting blood sugar was done using 2ML-Fluoride Oxalate blood tube. This assay was done using an automated Chemistry analyzer (Selectra Pro-S). The data were analyzed using SPSS for Windows version 25.0. A total of 200 participants including 40 diabetic males, 60 diabetic females, 48 non-diabetic males, and 52 non-diabetic females were recruited for the study. The values of FBS and MCHC were significantly higher in the diabetic male and female group. The mean values of PCV and MCV were significantly higher in both male and female non-diabetic group. The values of HB, RBC, and PLT-CT were also significantly lower in diabetic male but not significantly in females. There were 48% cases of anaemia among diabetic females 27% among non-diabetic females whereas only 13% anaemia was seen for diabetic males. Hematological parameters should be evaluated and treated periodically in both male and female diabetic patients to reduce the burden of DM and ocular morbidity due to retinopathy.

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