Ameliorating the Aphrodisiac Effect of Stephania wightii Arn. (Dunn) on Animal Model

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DOI: 10.21522/TIJAR.2014.03.01.Art021

Authors : Danya U.


Stephania wightii is an endemic medicinal plant traditionally used in India for various ailments. This study was set out to evaluate the aphrodisiac properties of methanolic aerial parts and tuber extracts of Stephania wightii using animal models. The methanolic tuber extract of S. wightii at the dose of 100 mg/kg body weight showed significant aphrodisiac activity on male wistar albino rats as evidenced by an increased the levels of reproductive hormones serum testosterone, Serum Luteinizing hormone and Serum Follicle-stimulating hormone. The efficiency was higher in the extract treated animals compared to the standard drug treated animal.


[1.] Yakubu M.T., A.M. Akanji and A.T. Oladiji, 2005. Aphrodisiac potentials of the aqueous extract of Fadogia agrestis (Schweinf. Ex Hiern) stem in male albino rats. Asian J. Androl., 7: 399-404.

[2.] Gaur R.D., 1999. Flora of district Garhwal North West Himalaya (with ethnobotanical notes) Ist ed. Transmedia Srinagar Garhwal, India, pp: 76-77.

[3.] Chopra R.N., I.C. Chopra, K.L. Handa and L.D. Kapur, 1958. Chopra’s Indigenous Drugs of India, 2nd ed. Char UN and Sons, Ltd., Calcutta, India, pp: 412.

[4.] Tietz N.W., 1995. Clinical guide to laboratory tests, 3rd edition, (Ed) W. B. Saunders, Philadelphia, pp: 578-580.

[5.] Aversa A and A. Fabbri, 2001. New oral agents for erectile dysfunction: what is changing in our practice? Asian J. Androl., 3: 175-179.

[6.] Morales A., 1996. Androgen supplementation in practice: the treatment of erectile dysfunction associated with hypotestosteronemia. In: Oddens BJ, Vermeulen A, (Eds). Androgens and aging male. London: Parthenon Publishing Group, pp: 233-45.

[7.] Pardridge W. M., 1986. Serum bioavailability of sex steroid hormones. Clin Endocrinol Metab, 15: 259-278.