Abstract:

The cultivation of human pathogens in experimental animals have made enormous contribution to the understanding and treatment of many diseases of humans. Even though the Mycobacterium leprae was one of the first human bacterial pathogens to be identified, has not been cultivated in vitro till 1960. The long delay in developing appropriate animal models of leprosy, hindered the progress in leprosy research. The long search for an animal model for leprosy has involved almost 30 species of animals and almost as many protocols as research.

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