The cultivation of
human pathogens in experimental animals have made enormous contribution to the
understanding and treatment of many diseases of humans. Even though the Mycobacterium leprae was one of the
first human bacterial pathogens to be identified, has not been cultivated in
vitro till 1960. The long delay in developing appropriate animal models of
leprosy, hindered the progress in leprosy research. The long search for an
animal model for leprosy has involved almost 30 species of animals and almost
as many protocols as research.
[1.] Abstracts from Tropical disease Bulletin, experimental
leprosy in monkeys. Indian Journal of Leprosy, V 68(4), 389-390
[2.] Clostan M.J, Adams L.B,(1998) .Report of workshop
pathogenesis and lessons from Leprosy. International Journal of Leprosy Dec
V 66 (4) P, 597-598.
[3.] Job. C. K., (2000). Developments in experimental
Leprosy: Indian Journal of Leprosy, V-72,145-154.
[4.] Peter, A.S., Johnstone, (1987). The search for animal
models of leprosy. International Journal of Leprosy, V 55(3), 535-547.
[5.] Rees, R. J. W., (1988). Animal models in Leprosy: British
Medical Bulletin V-44/3, 650-664.
[6.] Rees, R. J. W., (1991). Evolution and contribution of
animal model in Leprosy: Indian Journal of Leprosy V-63. 446-450.
[7.] Shetty V.P., Anitha N.H (1996). Animal Model For
Leprous neuropathy. Indian Journal of leprosy, V 68(1), 95-104.
[8.] Truman R.W, Krahenbul J.L, Viable M.(2001). Leprae as
a research reagent. International Journal of Leprosy, March, V 69(1) ,