Knowledge and Perceptions of Parents of Children Targeted for Cervical Cancer Immunization in Burkina Faso : The Case of the Manga, Kampti and Koupela Health Districts, August 2025
Abstract:
The vaccination is a fundamental pillar of disease prevention. As part of strengthening its Expanded Program on Immunization (EPI), Burkina Faso recently introduced two new vaccines in 27 pilot districts : the malaria vaccine (VAP) and the human papilloma virus (HPV) vaccine. Despite this progress, vaccination coverage remains below national targets in several districts. Based on lessons learned from the introduction of new vaccines in other African countries, we conducted an assessment of the challenges related to the acceptability and availability of these vaccines in three selected districts (Manga, Kampti, and Koupela). Mixed-methods study, combining qualitative and quantitative approaches, was conducted in three health districts. The qualitative component explored the knowledge, perceptions, and attitudes of parents of target children regarding vaccination against malaria and cervical cancer. Data were collected using Kobo Collect and analyzed with NVivo. Some participants (13/15) had their children vaccinated against HPV, while two parents had children who were not vaccinated. Furthermore, most parents mentioned reluctance towards this vaccine within their communities; hesitation linked to rumors, lack of information, and sociocultural perceptions. In conclusion, the Improving vaccine acceptability and availability requires strengthening community communication, improving the quality of reception, and supplying facilities with vaccines and inputs according to their needsReferences:
[1].
Diop, et al.,
2017,
Innovations en vaccinologie: enjeux et perspectives pour l’Afrique. Pan Afr
Med J 26. https://doi.org/10.11604/pamj.2017.26.235.11527
[2]. Shattock, et al.,
2024,
Contribution of vaccination to improved survival and health: modelling 50 years
of the Expanded Programme on Immunization. The Lancet S014067362400850X.
https://doi.org/10.1016/S0140-6736(24)00850-X.
[3].
Kaur,
G., Casey, R. M.,
Patel, J. C.,
Bloem, P., Walldorf, J. A.,
Hyde, T. B.,
2023,
Status of New Vaccine Introduction - Worldwide, 2016-2021. MMWR Morb Mortal
Wkly Rep 72, 746–750. https://doi.org/10.15585/mmwr.mm7227a2
[4]. MacDonald, N., Mohsni, E., Al-Mazrou, Y.,
Kim Andrus, J., Arora, N., Elden, S., Madrid, M.-Y., Martin, R., Mahmoud
Mustafa, A., Rees, H., Salisbury, D., Zhao, Q., Jones, I., Steffen, C. A., Hombach, J., O’Brien, K. L., Cravioto, A., 2020, Global vaccine action plan lessons learned
I: Recommendations for the next decade. Vaccine 38, 5364–5371. https://doi.org/10.1016/j.vaccine.2020.05.003
[5]. Sambala, E. Z., Wiyeh, A. B., Ngcobo, N., Machingaidze, S., Wiysonge,
C. S.,
2019,
New vaccine introductions in Africa before and during the decade of vaccines -
Are we making progress? Vaccine 37, 3290–3295. https://doi.org/10.1016/j.vaccine.2019.05.002.
[6]. Osoro, C. B., Ochodo, E., Kwambai, T. K., Otieno, J. A., Were, L., Sagam, C. K., Owino, E. J., Kariuki, S., Ter Kuile, F. O., Hill, J., 2024, Policy uptake and implementation of the
RTS,S/AS01 malaria vaccine in sub-Saharan African countries: status 2 years
following the WHO recommendation. BMJ Glob Health 9, e014719. https://doi.org/10.1136/bmjgh-2023-014719.
[7]. Adeyanju, G. C., Essoh, T.-A., Sidibe, A. R., Kyesi, F., Aina, M., 2024, Human Papillomavirus Vaccination
Acceleration and Introduction in Sub-Saharan Africa: A Multi-Country Cohort
Analysis. Vaccines 12, 489. https://doi.org/10.3390/vaccines12050489.
[8]. Kiendrébéogo, J. A., Sidibe, A. R.
O., Compaoré, G.
B., Nacanabo, R., Nawaz, S., Schuind, A. E., Clark, A., 2023, Cost-effectiveness of human papillomavirus
(HPV) vaccination in Burkina Faso: a modelling study. BMC Health Serv Res
23, 1338. https://doi.org/10.1186/s12913-023-10283-3.
[9]. Meda, Z. C., Hien, H., Traore, T. I., Ouattara, C. A., Ramde, Z., Ilboudo, B., Some, D. A., Ouattara, S., 2024, Factors associated with positive human
papillomavirus (HPV) test results in cervical precancer screening: a
cross-sectional study at Souro Sanou National Teaching Hospital (SSNTH) in Bobo
Dioulasso, Burkina Faso. BMC Public Health 24, 2900. https://doi.org/10.1186/s12889-024-20389-w.
[10]. Diendéré,
J., Kiemtoré, S., Coulibaly, A., Tougri, G., Ily, N. I., Kouanda, S., 2023, Low attendance in cervical cancer
screening, geographical disparities and sociodemographic determinants of
screening uptake among adult women in Burkina Faso : results from the
first nationwide population-based survey. Rev Epidemiol Sante Publique
71, 101845. https://doi.org/10.1016/j.respe.2023.101845.
[11]. Zabre, P., Sagna, T., Ouedraogo, R.,
Simpore, J., 2024, Epidemiological
profile of human papillomavirus infections and cervical cancer prevention among
sexually active women in Burkina Faso: Literature Review. MRAJ 12. https://doi.org/10.18103/mra.v12i11.5883.
[12]. Wilson,
R., 2021, HPV
vaccine acceptance in West Africa: A systematic literature review. Vaccine
39, 5277–5284. https://doi.org/10.1016/j.vaccine.2021.06.074.
[13]. Naba, C., Ishidaira, H., Magome, J., Souma,
K., 2024,
Exploring the Potential of Soil and Water Conservation Measures for Climate
Resilience in Burkina Faso. Sustainability 16, 7995. https://doi.org/10.3390/su16187995.
[14]. Pison, G., Poniakina, S., 2024, The population of the world (2024). Population
& Societies 626, 1–8. https://doi.org/10.3917/popsoc.626.0001.
[15]. Zongo, D., Tiendrebeogo, J. M.
A., Ouedraogo, W.
M., Bagayan, M., Ouedraogo, S. H., Bougouma, C., Nassa, C., Serme, M.,
Naré, D., Zida, A., 2025,
Epidemiological situation of schistosomiasis in 16 districts of Burkina Faso
after two decades of mass treatment. PLOS Neglected Tropical Diseases
19, e0012858. https://doi.org/10.1371/journal.pntd.0012858
[16]. Guenou, et al., 2024,
Acceptability and Feasibility of Human Papillomavirus Vaccine Introduction in
Cameroon: A Mixed-Methods Study. Cureus 16, e60723. https://doi.org/10.7759/cureus.60723.
[17]. Tran, et al., 2023,
Understanding barriers and motivations to papillomavirus vaccination in a
middle school in Reunion Island. Eur J Obstet Gynecol Reprod Biol 285,
17–23. https://doi.org/10.1016/j.ejogrb.2023.03.033.
[18]. Guillaume, et al., 2023,
Acceptability of an integrated school-based HPV
vaccination program within two districts of Tanzania: A qualitative descriptive
study. PLOS Global Public Health 3, e0001394. https://doi.org/10.1371/journal.pgph.0001394.
[19]. Wilson, R. J., Leigh, L., Bah, H., Larson, H. J., Clarke, E., 2023, HPV vaccination acceptance and perceptions
related to fertility and population control in the Gambia: An anthropological
analysis. Vaccine 41, 3647–3654. https://doi.org/10.1016/j.vaccine.2023.04.072.
[20]. Fisher, et al., 2024, Information needs of ethnically diverse, vaccine-hesitant parents during decision-making about the HPV vaccine for their adolescent child: a qualitative study. BMC Public Health 24, 91. https://doi.org/10.1186/s12889-023-17540-4.
