obstetric anaesthesia recommends that caesarean sections are done under regional
anaesthesia, but there are conditions for which regional anaesthesia is contraindicated,
so in those conditions general anaesthesia is the only choice.
general anaesthesia thiopental 4-5mg/kg l and propofol 2,5mg/kg are both used for
we have reviewed articles from 1989 up to 2016 comparing the use of thiopental to
propofol in caesarean sections.
a total of 20 published articles and abstracts from 1989 up to 2016 were reviewed.
These articles show that propofol was the best alternative drug for general anaesthesia
induction in caesarean section and has few disadvantages according to the neonate
Apgar score at one minute.
these articles reviewed show that propofol is currently the most commonly used induction
agent and alternative for obstetric general anaesthesia and has better neonatal
and maternal outcomes post operation than thiopental.
propofol, obstetric anaesthesia, thiopental, caesarean section
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randomized comparison of the effects of thiopental and propofol on bispectral index
during caesarean section till delivery of new-born. 2012.
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A, &Dadras MA. Comparing propofol with sodium thiopental on neonatal Apgar score
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. Mahjoobifard M et al. The comparison of
propofol with thiopental as induction drug on neonatal Apgar during elective cesarean
section. Zahedan J Res Med Sci (Zahedan Journal of Research in medical sciences)
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induction of anesthesia for elective Caesarean section. 1989.
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. Perisa Golfam et al. The effect of propofol
and thiopental on apgar score during caesarean section. 2009.
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. South African guidelines for safe use
of procedural sedation and analgesia for diagnostic and therapeutic procedures in
. Tiffany Sun Moon &Joshua Sappenfield
Anaesthesia management and challenges in the pregnant patient. 2016; 6:89-94.
. Tumukunde et al. The effect of propofol
versus thiopental on Apgar scores in newborns and peri-operative outcomes of women
undergoing emergency caesarean section: a randomized clinical trial. 2015.
. Update on use of propofol and thiopental
. Which induction drug for cesarean section?
A comparison of thiopental sodium, propofol, and midazolam.
. Vedat et al. Comparison of the effect of thiopental sodium and propofol on haemodynamics, awareness and newborns during caesarean section under general anaesthesia 2015. Turk Journal of anaesthesia reanimation.
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