Abstract:

Background: Although the government-initiated interventions to address the risk of diet-related non-communicable diseases, the prevalence of T2DM is still high, we conducted this study to determine the magnitude of T2DM and associated risk factors among health workers in Bariadi Town Council Tanzania.

Methodology: A cross-sectional study approach was applied for 229 participants. Qualitative variable was measured using proportion and quantitative variable were measured using mean and median. Strength of association was assessed by Odds Ratios with their corresponding 95% confidence interval. Both bivariable and multivariable logistic regression was used.

Results: The overall prevalence was found to be 7.9% (95%CI=4.7-12.1). Risk factors for T2DM were found to be sex (OR=4.545, 95%CI: 1.069-19.325), age between 30-41 and 41-50 years (OR=8.08, 95%CI: 1.215-53.741; OR=15.08, 95%CI: 2.315-98.342) and history of raised blood sugar (OR=0.032, 95%CI: 0.006-0.167).

Conclusion: Prevalence of T2DM was found to be high, female having higher than male. Sex, age, history of diabetes had significant association with T2DM. Control efforts should be directed on screening and public nutrition programmes.

Keywords: Diabetes Mellitus; Non-Insulin; Risk factors; prevention.

References:

[1].      World Health Organization (2014). Global Status Report on Noncommunicable Diseases 2014. Geneva, Switzerland. [www.who.int/ncd] site visited on 10/08/2016.

[2].      IDF (2013). Diabetes Atlas: Follow-up to the Political Declaration of the High-level Meeting of the General Assembly on the Prevention and Control of Non-communicable Diseases. Rio de Janeiro, Brazil. [www.idf.org/diabetesatlas] site visited on 16/07/2016.

[3].      Mayige, M., Kagaruki, G., Ramaiya, K. and Swai, A. (2012). Non communicable diseases in Tanzania: a call for urgent action. Tanzania Journal of Health Research, 14(2): 1–12.

[4].      Peer, N., Kengne, A. P., Motala, A. A. and Mbanya, J. C. (2014). Diabetes in the Africa region: An update. Diabetes Research and Clinical Practice, 103(2): 197–205.

[5].      World Health Organization (2005). Preventing Chronic Diseases: A Vital Investment. World Health Organization. Geneva, Switzerland. [http://www.who.int/chp/ chronic_disease_report/en/] site visited on 10/08/2016.

[6].      National Bereau of Statistics (2014). 2012 Population and Housing Census: Population Distribution by Administrative Areas (Vol. I). Dar es Salaam, Tanzania: National Bereau of Statistics. [http://www.nbs.go.tz] site visited on 12/08/2016.

[7].      Kothari, C. (2004). Research methodology: methods and techniques. New Age International (Second Rev). New Delhi, India: New Age International (P) Limited.

[8].      Ruhembe, C. C., Mosha, T. C. E. and Nyaruhucha, C. N. M. (2014). Prevalence and awareness of type 2 diabetes mellitus among adult population in Mwanza city, Tanzania. Tanzania Journal of Health Research, 16(2): 1–11.

[9].      Bennett, S., Woods, T., Liyanage, W. M. and Smith, D. L. (1991). Simplified general Method for Cluster-Sample Surveys of Health in Developing Countries. World Health Statistics Quarterly, 44(3): 98–106.

[10].  National Institutes of Health (NIH) (1998). Clinical guidelines on the identification, evaluation, and treatment of overweight and obesity in adults. The Evidence Report, NIH Publication No. 98-4083.National Institutes of Health (Vol. 158). Washington DC, USA. [https://hearttruth.gov/health/public/heart/obesity/wecan/ portion/documents/CORESET1.pdf] site visited on 18/07/2016.

[11].  Sforza, V. F. (2003). 2003 European Society of Hypertension – European Society of Cardiology guidelines for the management of arterial hypertension. Journal of Hypertension, 21(6): 1011–1054.

[12].  World Health Organization (2005a). Clinical Guidelines for the Management of Hypertension. (S. Oussama, M. N. Khatib, Mohamed, Ed.). Metropole, Cairo: WHO Libarary Cataloguing in Publication Data.

[13].  WHO (2006). Basic epidemiology: measuring of Health and Diseases. (K. Bonita.R, Beaglehole. R, Ed.) World Health Organization (2nd ed.). Geneva, Switzerland: WHO Libarary. 211pp.

[14].  Hosmer, D.W and Lemshow. S. (2013). Applied Logistic Regression. Second Edition. A Wiley-Interscience publication. John Wiley & Sons Inc. New York, US. available at [ [http:/resource.heartonline.cn/20150528/1_3kOQSTg.pdf].

[15].  Prem-Kumar, B., Hayati, K. and Rampal, L. (2014). Prevalence of Type 2 Diabetes Mellitus and its Associated Factors among a Public University Staff in Selangor. International Journal of Public Health and Clinical Sciences, 1(1): 118–130.

[16].  Erasmus, R. T., Soita, D. J., Hassan, M. S., Blanco-Blanco, E., Vergotine, Z., Kengne, A. P. and Matsha, T. E. (2012). High prevalence of diabetes mellitus and metabolic syndrome in a South African coloured population: Baseline data of a study in Bellville, Cape Town. South African Medical Journal, 102(11): 841–844.

[17].  Sacerdote, C., Ricceri, F., Rolandsson, O., Baldi, I., Chirlaque, M. D., Feskens, E. and Wareham, N. (2012). Lower educational level is a predictor of incident type 2 diabetes in European countries: The EPIC-interact study. International Journal of Epidemiology, 41(4): 1162–1173.

[18].  Ross, N. A., Gilmour, H., Dasgupta, K., Ross, N. A., Gilmour, H. and Dasgupta, K. (2010). 14-year diabetes incidence: the role of status socio-economic status. Health Report, Canada, 21(3): 1–28.

[19].  Connolly, V., Unwin, N., Sherriff, P., Bilous, R. and Kelly, W. (2000). Diabetes prevalence and socioeconomic status: a population-based study showing increased prevalence of type 2 diabetes mellitus in deprived areas. Journal of Epidemiology and Community Health, 54(3): 173–177 5.

[20].  Espelt, A., Borrell, C., Roskam, A. J., Rodriguez-Sanz, M., Stirbu, I., Dalmau-Bueno, A. and Kunst, A. E. (2008). Socioeconomic inequalities in diabetes mellitus across Europe at the beginning of the 21st century. Diabetologia, 51(11): 1971–1979.

[21].  Basu, R., Breda, E., Oberg., A. L., Claudia, C. P., Chiara, D. M., Vittone, A. B., George, J. L., Klee. G., Puneet, A., Michael, D. and Jensen, G. T. (2003). Mechanisms of the Age-Associated Deterioration in Glucose Tolerance: Contribution of Alterations in Insulin Secretion, Action, and Clearance. Diabetes, 52(7): 1738–1748.

[22].  Gambert, S. R. and Pinkstaff, S. (2006). Emerging epidemic: Diabetes in older adults: Demography, economic impact, and pathophysiology. Diabetes Spectrum, 19(4): 221–228.

[23].  Whiting, D. R., Guariguata, L., Weil, C. and Shaw, J. (2011). IDF Diabetes Atlas: Global estimates of the prevalence of diabetes for 2011 and 2030. Diabetes Research and Clinical Practice, 94(3): 311–321.

[24].  Shaw, J. E., Sicree, R. A. and Zimmet, P. Z. (2010). Global estimates of the prevalence of diabetes for 2010 and 2030. Diabetes Research and Clinical Practice, 87(1): 4–14.

[25].  WHO (2016). GLOBAL REPORT ON DIABETES. Paris, France. Retrieved from [http://www.who.int] site visited on 12/02/2017.

[26].  Perreault, L., Marrero, D., Ma, Y., Crandall, J., Dagogo-Jack, S., Barrett-Connor, E. and Horton, E. (2008). Sex Differences in Diabetes Risk and the Effect of Intensive Lifestyle Modification in. Diabetes Care, 31(7): 1416–1421.

[27].  Leslie, L. K., Cohen, J. T., Newburger, J. W., Alexander, M. E., Wong, J. B., Sherwin, E. D. and Triedman, J. K. (2005). The relationships Between Testosterone, Body Composition, and Insulin Resistance: A lesson from a case of extreme hyperondrogenism. Diabetes Care, 28(2): 429–432.

[28].  Nordström, A., Hadrévi, J., Olsson, T., Franks, P. W. and Nordström, P. (2016). Higher Prevalence of Type 2 Diabetes in Men Than in Women Is Associated with Differences in Visceral Fat Mass. The Journal of Clinical Endocrinology and Metabolism, 101(10): 3740–3746.

[29].  Mutebi, E., Nakwagala, F. N., Nambuya, A. and Otim, M. (2012). Undiagnosed diabetes mellitus and impaired glucose tolerance among hypertensive patients in Mulago Hospital, Kampala, Uganda. African Journal of Diabetes Medicine, 20(1): 20–23.

[30].  Safari, M., Yazdanpanah, B., Yazdanpanah, B. and Mobasheri, A. (2014). A Population-based Screening of Type 2 Diabetes in High-risk Population of Yasuj, Iran. Journal of Health, Population and Nutrition, 32(4): 677–686.

[31].  Nathan, D. M., Davidson, M. B., DeFronzo, R. A., Heine, R. J., Henry, R. R., Pratley, R. and Kahn, R. (2007). Impaired fasting glucose and impaired glucose tolerance: Implications for care. Diabetes Care, 30(3): 753–759.

[32].  Tuomilehto J., Indstrom J., Eriksson J., Valle T., H. E. and U. M. (2001). Prevention of Type 2 Diabetes Mellitus by Changes in Lifestyle Among Subjects with Impaired Glucose Tolerance. The New England Journal of Medicine, 344(18): 1343–1350.

[33].  Laramee, A. S., Morris, N. and Littenberg, B. (2007). Relationship of literacy and heart failure in adults with diabetes. BMC Health Services Reserch, 7(98): 1–6.

[34].  Mohan, V., Sandeep, S., Deepa, R., Shah, B. and Varghese, C. (2007). Epidemiology of type 2 diabetes: Indian scenario. Indian J. Med Res, 125(3): 217–230.

[35].  Weiss, B. (2007). Health literacy and patient safety: Help patients understand. Manual for clinicians. (Second Edi). Arizona, USA: American Medical Association Foundation and American Medical Association.

[36].  Farshchi, H. R., Taylor, M. A. and Macdonald, I. A. (2005). Deleterious effects of omitting breakfast on insulin sensitivity and fasting lipid profiles in healthy lean women 1 – 3. American Journal of Clinical Nutrition, 81: 388–396.

[37].  Uemura, M., Yatsuya, H., Hilawe, E. H., Li, Y., Wang, C., Chiang, C. and Aoyama, A. (2015). Breakfast Skipping is Positively Associated with Incidence of Type 2 Diabetes Mellitus: Evidence from the Aichi Workers’ Cohort Study. J Epidemiol, 25(5): 351–358.

[38].  Fritschi, C., Park, H., Richardson, A., Park, C., Collins, E. G., Mermelstein, R. and Quinn, L. (2016). Association Between Daily Time Spent in Sedentary Behavior and Duration of Hyperglycemia in Type 2 Diabetes. Biological Research for Nursing, 18(2): 160–166.

[39].  Wilmot, E. G., Edwardson, C. L., Achana, F. A., Davies, M. J., Gorely, T., Gray, L. J. and Biddle, S. J. H. (2012). Sedentary time in adults and the association with diabetes, cardiovascular disease and death: Systematic review and meta-analysis. Diabetologia, 55(11): 2895–2905.

[40].  British Heart Foundation National Centre (2012). Interpreting the UK physical activity guidelines for older adults (65+). Guidance for those who work with older adults described as actives. Loughbourough, UK. [www.bhfactive.org.uk] site visited on 14/07/2016.