Evaluation of HIV Seropositivity Among MDR-TB Adult Patients at Ndola Central Hospital
This paper evaluates HIV sero-positivity among Multi- Drug Resistance
Tuberculosis adult patients at Ndola Central Hospital, Ndola, Zambia.
question: How many patients who were admitted at Ndola Central Hospital had HIV
/ MDR- TB co-infections, and how many died?
A Retrospective Cohort study using the existing data and laboratory results in
patient files and MDR TB register (sampling frame) were reviewed for all MDR TB
patients whose culture and drug susceptibility test done at Ndola Central Hospital
were assessed for HIV sero-status from January 2010 to June 2014. Review of records
was done from 15/08//2014 to 22//o8/14 and sample comprised of 114 records
which were available during the stated period using convenient sampling. A semi-structured
questionnaire was used for data collection on the existing data base on
patient’s file and MDR- TB patient register. Data analyzed using Epi data
version 3 and bivariate analysis.
The study revealed that 68.1% of the MDR TB patients were males, compared to
31.9% females; however there was no association between MDR TB and sex. The study
showed that 42% of the respondents with MDR TB were co-infected with HIV. It
also revealed that mortality among HIV / MDR TB co-infected patients was 36%
and those negative accounted 12.7% showing an association between HIV sero
status and MDR TB co-infection mortality.
HIV / MDR TB co-infection is a major public health problem needing urgent
interventions, and proper treatment options for policy direction.
Evaluation, HIV / MDR-TB co-infection, Ndola, Zambia.
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. DOI: http://dx.doi.org/10.1016/j.tube.2013.08.009
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