aimed at determining prevalence of Multi Drug Resistance Tuberculosis at Ndola Central
Hospital among Adults, Ndola, Zambia.
retrospective cohort study review was conducted among adult MDR-TB patients at Ndola
Central Hospital from 15th August to 22nd August 2014. All
records for MDR TB patients from MDR TB ward were reviewed (January 2010 up to June
2014). Sample size was 114, Convenient sampling was done using MDR- TB treatment
register and laboratory results. Data was analyzed using Epi Data version 3, and
Pearson Chi square. The findings revealed that 48.2% of the patients with MDR TB
had sputum positive results for culture, compared to 6.6% whose sputum was negative.
The study also found that, of all (114) MDR TB patients who were admitted in MDR
TB ward at Ndola Central Hospital, only 44% had Multi drug resistance , 33% had
Mono resistance, while 22.6% had Poly resistance. The findings revealed that 29.8%
were new cases, 23.7% treatment failure, and 4.9% relapse. Discussion of findings
shows that; almost 50% of the respondents had MDR TB which was confirmed by sputum
culture results and others had poly resistance and mono resistance. The respondents
were either new cases, treatment failure or relapse cases, which showed that there
could be other factors associated with drug resistance.
prevalence rate of MDR TB was 44% and is major threat for TB control measures and
proper treatment options.
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