Relationship Between Osteoprotegerin and Sclerostin with Bone Metabolism in Obese Men
Abstract:
A series of experiments were conducted to measure various anthropometric and biological indicators for each group. Height and weight were measured to calculate BMI, as were waist circumference to measure abdominal fat accumulation. Waist-to-hip ratio (WHR) and waist-to-height ratio (WHtR) were also measured to determine body fat distribution. Lipid analyzers were used to accurately measure body fat percentage, while laboratory techniques were used to measure blood levels of osteoprotegerin and sclerostin. Regarding biological markers, the study showed that osteoprotegerin and sclerostin levels increased inversely with increasing body mass index (BMI), suggesting a role for these proteins and hormones in the metabolic effects associated with obesity. These findings highlight the potential of using these biomarkers to assess health risks associated with obesity and determine appropriate treatment strategies.The study concluded that using body mass index (BMI) alone to assess health risks may be insufficient, as it does not reflect the distribution of body fat. Therefore, it is preferable to use a combination of anthropometric indicators such as waist circumference, WHR, WHtR, and body fat percentage to provide a comprehensive assessment of health risks associated with obesity. The results also indicate that individuals with increased waist circumference and WHR are more likely to develop heart disease and diabetes.References:
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