Prevalence of Urinary Tract Infection (Uti) and Antimicrobial Susceptibility Pattern among Patients Attending National Hospital Abuja, Fct - Nigeria

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Authors : Adedamola Amos Ogundeji



Urinary Tract Infection (UTI) is a significant health problem worldwide, affecting all ages and both sexes. Hence, the need for determination of microorganisms causing urinary tract infection (UTI) and their in-vitro susceptibility test is of paramount important to improve service delivery to patients. With this background, a retrospective study was carried out from July 2013 to December 2013 at National Hospital Abuja (NHA).


This study is planned to determine the prevalence of urinary tract infection (UTI) among different sexes and age groups as well as the predominant bacterial pathogens and their sensitivity to antibiotics so as to guide empirical antibiotic therapy. This is aimed at providing improved patient care and management.


A total of 2640 urine samples from patients attending both inpatient and Outpatient departments of NHA were included in this study. Data of all patients who had positive urine culture between July 2013 and December 2013 were systematically and retrospectively collected from the Laboratory register of the Medical Microbiology and Parasitology Department. Demographic data of these selected individuals’ patient, sex, marital status, pathogens isolated and their antimicrobial sensitivity pattern were collated and analyse. These urine samples were earlier subjected to culture and sensitivity test with the use of standard bacteriological techniques as described by American Society for Microbiology (ASM).


Twenty five percent of the total urine samples (2640) showed significant bacterial growth. Ten different bacterial species were isolated. Among these, Escherichia coli (49.5%) was significantly the most predominant one (P<0.05) followed by Staphylococcus aureus (14.9%), Klebsiella spp (11.8%), Enterococcus faecalis (8.9%), Pseudomonas aeruginosa (4.4%), Proteus spp (3.3%) and others. Majority of Gram-negative bacteria showed susceptibility towards Ciprofloxacin, Gentamicin, and Amikacin. The age group with highest frequency of UTIs was 21–30 years with females predominating in all the age groups except in less than 1 and above 60 years (Fig. 7). The results showed that married women are more likely to be affected than their single or widowed counterparts while the reverse was the case in males (Fig. 8).


This outcome of this study shows that there is need for more work in this area be to consistently determine the changing pattern of microbial uropathogens and their antimicrobial profiles.


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