Effectiveness of Prevention of Mother-to-Child Transmission of HIV Program in Benue, Nigeria

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DOI: 10.21522/TIJPH.2013.07.04.Art001

Authors : Plang Jwanle, Ademola Amosu, Emerenini Franklin C


Introduction: Over 90% of HIV infections in children are acquired through the mother-to-child transmission route. Mother to child transmission can be prevented through use of efficacious antiretroviral drug regimens and complete avoidance of breastfeeding. This study evaluated the effectiveness of PMTCT program in Benue State, Nigeria.

Methods: This was a retrospective study of infants and children perinatally exposed to HIV aged 6 weeks -18 months from Benue State, Nigeria. 5734 consecutive sample of infants and children identified from the EID laboratory register from January 2017-December 2017 were enrolled for this study. The details of ARV therapy commencement for mother and baby, infant feeding choices, and HIV PCR DNA test results were analyzed using SPSS version 20.

Result: 225 out of 5734 exposed babies tested positive to HIV giving an overall prevalence of 3.9% (95% CI: 3.4 -4.4). When neither mother nor baby received ARVs the prevalence was 33%; when only baby received ARVs the prevalence was 10.8%; when only mother received ARVs the prevalence was 9.1% and when both mother and baby received ARV for PMTCT the prevalence reduced to 1.5%.

Conclusions: This study has shown the usefulness of ARVs as the single most important intervention in PMTCT. There was a high prevalence of HIV among exposed children in our setting, especially if the mother and child pairs did not receive any form of antiretroviral prophylaxis. Therefore, there is need to expand antiretroviral coverage, ensure access of the PMTCT program, and provide effective services to support infected children.

Keywords: prevention of mother-to-child HIV transmission, PMTCT, HIV, antiretroviral prophylaxis.


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