resistant tuberculosis (MDR-TB) is one of the greatest challenges to controlling
tuberculosis worldwide, Nigeria
inclusive. We conducted a descriptive, cross-sectional
study to identify and access the enrollment rate of MDR-TB cases in 2017 in Kano
state, north west Nigeria
We reviewed the MDR-TB
patients line list of Kano state tuberculosis and leprosy control program (TBLCP)
using the National TBLCP line listing template. The data was analyzed using Epi
Info version 3.5.4 and Microsoft Excel 2007.
total of 121 MDR TB cases were managed in the year 2017 in Kano state, of which
115 (95.0%) were identified within the year, 5 (4,1%) were referred in from other
states, 1 (0.9%) carried over to the year. Of the 121 cases managed, 82 (67.8%)
were males. Of the 121 cases managed in the year 2017, 77 (63.6%) were enrolled,
3 (2.5%) died before enrolment, 5 (4.1%) refused treatment and 14 (11.6%) loss to
follow up. The highest number of MDR cases managed, 38 (31.4%) was in Q3 while Q1
had the lowest number of cases managed as 20 (16.5%). Q3 had the highest enrollment
rate of 89.5% (34/38) while Q4 had the lowest enrollment rate of 17.9% (5/28).
MDR TB enrollment rate in Kano state in 2017 is low. Majority of the cases were
enrolled in Q3 of the year. There is high rate of loss to follow up. There is need
for Kano TBLCP to institute prompt identification of cases for immediate enrollment.
Assessment, enrollment rate, Multidrug-resistant
tuberculosis, Kano state, north west Nigeria.
Health Organisation. Multidrug and extensively drug-resistant TB. Indian J Tuberc.
2010;57(4):180–91. Available from: http://www.ncbi.nlm.nih.gov/pubmed/21141336.
. Federal Ministry of
Health of Ethiopia: Guideline for program and clinical management of drug resistant
tuberculosis. 5th edition. Addis Ababa, Ethiopia: FMOH; 2009.
. WHO: Anti-tuberculosis
drug resistance in the world. Third global report. The WHO/IUATLD Global Project
on Ant tuberculosis Drug Resistance Surveillance, 1999–2002. Geneva: World Health
. Ahuja SD, Ashkin D,
Avendano M, et al. Multidrug resistant pulmonary tuberculosis treatment regimens
and patient outcomes: an individual patient data meta-analysis of 9,153 patients.
PLoS Med 2012;9: e1001300.
. Fawcet t IW, Watkins
BJ. Initial resistance of Mycobacterium tuberculosis in Northern Nigeria
Tubercle 1976; 57:71-3.
. World Health Organization
(WHO). Multidrug and extensively drug resistant TB (M/XDR-TB): 2012 global report
on surveillance and response (WHO/HTM/TB/2010.3). Geneva: WHO, 2012.
. World Health Organization.
Global Tuberculosis Control: WHO report 2016. Geneva, Switzerland: World Health
. The World Gazetteer.
Profile of Kano, the capital city of State. Archived from the original on 9 February2013.
Retrieved 2007-03-27. Accessed on 07/10/2019 from URL: http://www.http/kano/profile.
Health Organization. Guidelines for the programmatic management of drug-resistant
tuberculosis, 2011 update. WHO/HTM/TB/2011.1Geneva: WHO, 2011.
Health Organization. Global tuberculosis report 2015. WHO/HTM/TB/2015.54. Geneva:
J, Wei X, Li H, Sun K, Zhang Z, Chen P, et al. Study on barriers to anti-TB treatment
for rural-to-urban migrant TB patients in Shanghai. Chin J Antituberc 2009; 31:337–340. [Google Scholar].
Anti-tuberculosis Association. The Guideline for Drug-resistant
Chin J Antituberc
. Marra CA, Marra F, Cox VC. Factors influencing quality of life
in patients with active tuberculosis. Health Qual Life Outcomes 2004; 2:58.
. Olusoji D, Elutayo
O, Olanrewaju O, Olapade GD. Pre-extensive drug resistant TB among MDR-TB patients.
Global Advd Res J Microbiol. 2013; 2:22–5. [Google Scholar].