Vitamin D plays a crucial role in electrolytic reabsorption
and calcium homeostasis, thereby maintaining skeletal and extra-skeletal integrity.
In addition, the literature establishes its potency to prevent insulin-dependent
diabetes, cardiovascular diseases, malignancies, and various autoimmune disorders.
Therefore, determining vitamin D deficient states and its correlation with systemic
factors plays a notable role in clinical medicine. The present cross-sectional study was conducted to determine the Prevalence
and symptomatic correlation of vitamin D deficiency in individuals visiting an annual
health check-up at a quaternary care hospital, Lucknow, Uttar Pradesh, India. The study stipulated the
prevalence rate of serum vitamin D deficiency levels was 91 % among healthy individuals.
The overall mean value of serum vitamin D was 17.54 ng/mL. With 91.2 % symptomatic
individuals, the mean age of patients was 48.08 ± 10.33 years, with the majority
of males (61.53 %). The mild, moderate, and severe grades of vitamin D deficiency
were seen in 32.53 %, 53.01 %, and 14.45 % of study participants, respectively.
On applying Pearson correlation, there is a strong negative correlation between
the total symptom score (12.98) and serum vitamin D levels with an R-value of -0.788.
The study reveals the higher prevalence rate of vitamin D deficiency
among apparently healthy participants. The associated symptoms among moderate and
severe vitamin D deficient study participants indicate the alarming stage in the
country. The study concluded the need for comprehensive public health programs concerning
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