Prevalence and Association Between HIV PrEP Knowledge and Approval, and HIV Testing among Sexually Experienced Men in Côte d'Ivoire

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DOI: 10.21522/TIJPH.2013.12.01.Art009

Authors : Ikenna Obasi Odii, Edson Chipalo

Abstract:

Despite evidence of high interest and willingness to use PrEP by key populations behaviorally vulnerable to HIV infection, a lack of comprehensive PrEP knowledge and low HIV testing currently undermine HIV prevention efforts in Cote d’Ivoire. Given that HIV testing is the initial phase in the HIV prevention care continuum, this study examined the prevalence and association between HIV PrEP knowledge and HIV testing among sexually experienced men aged 15-59 years using the dataset from the 2021 Cote d’Ivoire Demographic and Health Survey (N=7,591). Prevalence estimates were obtained using frequencies and proportions. A multivariate logistic regression model was fitted to examine the relationship between the independent and dependent variables within the population. The findings reveal that merely 8.3% of the participants were aware of and endorsed PrEP, and 23.7% have undergone HIV testing. Yet, 83.8% of the participants reported being sexually active, with 32.8% involved in multiple sexual partnerships. Knowledge and approval of PrEP was a poor predictor of sexual activity (AOR=1.11, 95% CI=.81-1.53, p=.524), unlike HIV testing was strongly associated with higher odds of being sexually active (AOR=6.74, 95% CI=4.94-9.21, p<.001) in those who have undergone HIV testing. Knowledge of HIV test kits and anti-retroviral treatment were both strongly associated with higher odds of sexual activity and multiple sexual partnerships. To stem the tide of new HIV transmission, HIV Prevention initiatives should be prioritized among sexually active men by developing innovative approaches to scale up HIV testing and optimize comprehensive knowledge of PrEP in Cote d’Ivoire.


References:

[1] Phiri, M., et al., 2022, Examining differentials in HIV transmission risk behaviour and its associated factors among men in Southern African countries, Humanities and Social Sciences Communications, 9(1), p. 295.

[2] The Joint United Nations Programme on HIV and AIDS UNAIDS. Global HIV & AIDS statistics — Fact sheet, 2023 December 25, 2023; Available from: https://www.unaids.org/en/resources/fact-sheet.

[3] Irungu, E.M. and J.M. Baeten, 2020, PrEP rollout in Africa: status and opportunity, Nature Medicine, 26(5), p. 655-664.

[4] Ssuna, B., et al., 2022, Factors associated with willingness to use oral pre-exposure prophylaxis (PrEP) in a fisher-folk community in peri-urban Kampala, Uganda, BMC public health, 22(1), p. 468.

[5] Allan-Blitz, L.T., L.A. Mena, and K.H. Mayer, 2021, The ongoing HIV epidemic in American youth: challenges and opportunities, Mhealth, 7, p. 33.

[6] Eaton, L.A., et al., 2015, Minimal Awareness and Stalled Uptake of Pre-Exposure Prophylaxis (PrEP) Among at Risk, HIV-Negative, Black Men Who Have Sex with Men, AIDS Patient Care & STDs, 29(8), p. 423-429.

[7] Koss, C.A., et al., 2021, HIV incidence after pre-exposure prophylaxis initiation among women and men at elevated HIV risk: A population-based study in rural Kenya and Uganda, PLoS medicine, 18(2), p. e1003492.

[8] Ayieko, J., et al., 2021, Uptake and outcomes of a novel community‐based HIV post‐exposure prophylaxis (PEP) programme in rural Kenya and Uganda, Journal of the International AIDS Society, 24(6), p. e25670.

[9] Celum, C., et al., 2021, PrEP uptake, persistence, adherence, and effect of retrospective drug level feedback on PrEP adherence among young women in southern Africa: Results from HPTN 082, a randomized controlled trial, PLoS medicine, 18(6), p. e1003670.

[10] Matambanadzo, P., et al., 2021, “It went through the roof”: an observation study exploring the rise in PrEP uptake among Zimbabwean female sex workers in response to adaptations during Covid‐19, Journal of the International AIDS Society, 24, p. e25813.

[11] Becquet, V., et al., 2020, Sexual health needs of female sex workers in Côte d’Ivoire: a mixed-methods study to prepare the future implementation of pre-exposure prophylaxis (PrEP) for HIV prevention, BMJ open, 10(1), p. e028508.

[12] Nouaman, M.N., et al., 2022, Incidence of HIV infection and associated factors among female sex workers in Côte d’Ivoire, results of the ANRS 12361 PrEP-CI study using recent infection assays, Plos one, 17(11), p. e0271988.

[13] Ahouada, C., et al., 2020, Acceptability of pre-exposure prophylaxis (PrEP) among men who have sex with men (MSM) in Benin: A qualitative study, AIDS Care, 32(2), p. 242-248.

[14] Hill, L.M., et al., 2020, HIV risk, risk perception, and PrEP interest among adolescent girls and young women in Lilongwe, Malawi: operationalizing the PrEP cascade, Journal of the International AIDS Society, 23, p. e25502.

[15] Jackson-Gibson, M., et al., 2021, Facilitators and barriers to HIV pre-exposure prophylaxis (PrEP) uptake through a community-based intervention strategy among adolescent girls and young women in Seme Sub-County, Kisumu, Kenya, BMC public health, 21, p. 1-13.

[16] Duby, Z., et al., 2023, “These Girls Have a Chance to be the Future Generation of HIV Negative”: Experiences of Implementing a PrEP Programme for Adolescent Girls and Young Women in South Africa, AIDS and Behavior, 27(1), p. 134-149.

[17] Pasipanodya, E.C., et al., 2021, “PrEP” ing for a PrEP demonstration project: understanding PrEP knowledge and attitudes among cisgender women, BMC women's health, 21(1), p. 220.

[18] Malone, J., et al., 2021, Perceived HIV acquisition risk and low uptake of PrEP among a cohort of transgender women with PrEP indication in the eastern and southern United States, JAIDS Journal of Acquired Immune Deficiency Syndromes, 88(1), p. 10-18.

[19] Musheke, M., et al., 2013, A systematic review of qualitative findings on factors enabling and deterring uptake of HIV testing in Sub-Saharan Africa, BMC public health, 13(1), p. 1-16.

[20] Chikwari, C.D., S. Dringus, and R.A. Ferrand, 2018, Barriers to, and emerging strategies for, HIV testing among adolescents in sub-Saharan Africa, Current Opinion in HIV and AIDS, 13(3), p. 257-264.

[21] Hlongwa, M., et al., 2020, Barriers to HIV testing uptake among men in sub-Saharan Africa: a scoping review, African Journal of AIDS Research, 19(1), p. 13-23.

[22] Giguère, K., et al., 2021, Trends in knowledge of HIV status and efficiency of HIV testing services in sub-Saharan Africa, 2000–20: a modelling study using survey and HIV testing programme data, The Lancet HIV, 8(5), p. e284-e293.

[23] Kumwenda, M., et al., 2014, Factors shaping initial decision-making to self-test amongst cohabiting couples in urban Blantyre, Malawi, AIDS and Behavior, 18, p. 396-404.

[24] Guanira, J.V., et al., 2015, Streamlining HIV Testing for HIV Preexposure Prophylaxis, Journal of Clinical Microbiology, 53(1), p. 179-183.

[25] Smith, D.K., et al., 2012, Interim guidance for clinicians considering the use of preexposure prophylaxis for the prevention of HIV infection in heterosexually active adults.

[26] Grov, C., et al., 2021, How Has HIV Pre-Exposure Prophylaxis (PrEP) Changed Sex? A Review of Research in a New Era of Bio-behavioral HIV Prevention, The Journal of Sex Research, 58(7), p. 891-913.

[27] Cote d'Ivoire population-based HIV impact assessment CIPHIA. Results from National HIV Survey Indicate HIV Treatment Progress in Côte d’Ivoire and Identify Gaps in Testing Services. 2021 December 30, 2023]; Available from: https://phia.icap.columbia.edu/results-from-national-hiv-survey-indicate-hiv-treatment-progress-in-cote-divoire-and-identify-gaps-in-testing-services/.

[28] PrEP Watch. CÔTE D’IVOIRE Country Operational Plan (COP/ROP) 2022 Strategic Direction Summary. 2022 December 30, 2023]; Available from: https://www.prepwatch.org/resources/cote-divoire-cop-2022/.

[29] Centers for Disease Control and Prevention. Sexual Risk Behaviors. 2023 June 25, 2023]; Available from: https://www.cdc.gov/healthyyouth/sexualbehaviors/index.htm.

[30] Demographic and Health Survey. 2021 Cote d'Ivoire Demographic and Health Survey. 2022  December 30, 2023]; Available from: https://www.dhsprogram.com/publications/publication-FR385-DHS-Final-Reports.cfm.

[31] Kayesu, I., et al., 2022, Uptake of and adherence to oral pre-exposure prophylaxis among adolescent girls and young women at high risk of HIV-infection in Kampala, Uganda: A qualitative study of experiences, facilitators and barriers, BMC Women's Health, 22(1), p. 440.

[32] Jackson-Gibson, M., et al., 2021, Facilitators and barriers to HIV pre-exposure prophylaxis (PrEP) uptake through a community-based intervention strategy among adolescent girls and young women in Seme Sub-County, Kisumu, Kenya, BMC Public Health, 21(1), p. 1284.

[33] Laurent, C., et al., 2021, HIV pre-exposure prophylaxis for men who have sex with men in west Africa: a multicountry demonstration study, The Lancet HIV, 8(7), p. e420-e428.

[34] Fee, N., Youssef M., 1993, Young people, AIDS and STD prevention: experiences of pee approaches in developing countries.

[35] Ajuwon, A.J., 2005, Benefits of sexuality education for young people in Nigeria. in Understanding human sexuality seminar series, African Regional Sexuality Resource Centre Lagos.

[36] Diabaté, S., et al., 2021, Pre-exposure prophylaxis among men who have sex with men in Côte d’Ivoire: a quantitative study of acceptability, AIDS Care, 33(9), p. 1228-1236.

[37] Reyniers, T., et al., 2023, Strategies to improve PrEP uptake among West African men who have sex with men: a multi-country qualitative study, Frontiers in Public Health, 11, p. 1165327.

[38] Chandler, R., et al., 2020, The pre-exposure prophylaxis (PrEP) consciousness of black college women and the perceived hesitancy of public health institutions to curtail HIV in black women, BMC Public Health, 20(1).

[39] Eubanks, A., et al., 2022, Rate and Predictors of Ineffective HIV Protection in African Men Who Have Sex with Men Taking Pre-Exposure Prophylaxis, AIDS and Behavior, 26(11), p. 3524-3537.

[40] Stutts, L.A., et al., 2022, Lost in translation: College students’ knowledge of HIV and PrEP in relation to their sexual health behaviors, Journal of American College Health, 70(2), p. 561-567.

[41] Bulstra, C.A., et al., 2021, Integrating HIV services and other health services: A systematic review and meta-analysis, PLoS medicine, 18(11), p. e1003836.