Prevalence and Factors Responsible for Asymptomatic Malaria Reservoir of Plasmodium Falciparum Among Adults in Nasarawa State, Nigeria

Download Article

DOI: 10.21522/TIJPH.2013.12.01.Art033

Authors : Shamsudeen Abdulkareem, Akeyede, Imam

Abstract:

Asymptomatic malaria is prevalent in highly endemic areas of Africa, with only a small percentage of individuals exhibiting clinical symptoms. The clinical consequence of asymptomatic malaria is not fully understood. Some researchers are of the view that asymptomatic parasitaemia is involved in the development of partial immunity and may protect against clinical disease from new infections. The purpose of this study was to assess the prevalence of malaria reservoir of plasmodium falciparum among adult people of Nasarawa state of Nigeria and to identify the factors associated with malaria in this category of people. A community-based cross-sectional study was conducted among selected local government areas of the state. The outcome variable was the presence or absence of malaria in which its asscoiation with demographic information, knowledge and awareness, measures and control, environmental factors are tested. The local government areas were observed to have reported the highest positivity rate of malaria between 2017 to 2022. The study was conducted from August 2022 to April 2023. A semi-structured questionnaire was employed to collect socio-demographic data and other associated risk factors by trained health professionals. Body temperature and other clinical manifestations were examined to identify the asymptomatic individuals. This examination was carried out after selection of individuals from households before mRDT is conducted. Data entry and analysis was carried out using SPSS (Statistical Package for the Social Sciences) version 20 software. The results obtained are very desirable.

References:

[1] Christopher I., Alex B. Odaibo& David O.O., 2011, Impact of Asymptomatic Malaria on Some Hematological Parameters in the Iwo Community in Southwestern Nigeria, Med Princ Pract 2011;20:459–463, DOI: 10.1159/000327673. Avalable at https://www.academia.edu/52627888/Impact_of_Asymptomatic_Malaria_on_Some_Hematol ogical_Parameters_in_the_Iwo_Community_in_Southwestern_Nigeria

[2] Moonen B, Cohen J. M, Snow R. W, Slutsker L, Drakeley C, Smith D. L, Abeyasinghe RR, Rodriguez M. H, Maharaj R, Tanner M, Targett G, 2010, Operational strategies to achieve and maintain malaria elimi-nation. Lancet. 376(9752): 1592–603.DOI: https//10.1016/s0140-6736 (10), 61269-X

[3] Olukemi K. Amodu, Obioma C. Uchendu, 2014, https://www.researchgate.net/publication/271533876_Differences_in_the_Malariometric_Indices_of_Asymptomatic_Carriers_in_Three_Communities_in_Ibadan_Nigeria

[4] World Health Organization , 2020, World Malaria Report 2020. Available at https://www.who.int/publications/i/item/9789240015791

[5] Okafor F.U., and Oko-Ose J. N., 2012, Prevalence of malaria infections among children agedsix months to eleven years (6 months-11 years) in atertiary institution in Benin City, Nigeria. Global Advanced Research Journal of Medicine and Medical Sciences, 1(10): 273-279

[6] U.S. President’s Malaria Initiative (PMI): Nigeria Malaria Operational Plan FY 2023. Available at htpps://www.pmi.gov

[7] Ukpong I. G., Etim S. E., Ogban E. I., and Abua L. L., 2015, Prevalence of Malaria in the Highlands of Obudu Cattle Ranch, Nigeria, International Journal of Tropical Disease and Health,7(3): 87-93, https://doi.org/10.9734/IJTDH/2015/14609

[8] Wagbatsoma, V. A. and Ogbeide, O.,1995, Towards malaria control in Nigeria: A qualitative study on population of mosquitoes. The Journal of the Royal Society for the Promotion of Health, Vol. 115, No. 6, pp. 363–365. DOI: https://dx.doi.org/10.1177/146642409511500607

[9] Nwaneri D. U, Adeleye O. A, Ande A. B, Asymptomatic malaria parasitaemia using rapid diagnostic test in unbooked pregnant women in rural Ondo-south district , Nigeria. J Prev Med Hyg. 2013;54:49–52.

[10] Ellis Kobina Paintsil, Akoto Yaw Omari-Sasu, Matthew Glover Addo, and Maxwell Akwasi Boateng et al, 2019, Analysis of Haematological Parameters as Predictors of Malaria Infection Using a Logistic Regression Model: A Case Study of a Hospital in the Ashanti Region of Ghana. Hindawi Malaria Research and Treatment Volume 2019, Article ID 1486370, 7 pages, available at https://doi.org/10.1155/2019/1486370

[11] Severe Malaria Observatory , 2020, Knowledge sharing for malaria. Available at https://www.severemalaria.org/countries/nigeria

[12] World HealthOrganization , 2021, World Malaria Report 2021. Available at https://www.who.int/news room/fact-sheets/detail/malaria. Trans R Soc Trop Med Hyg; 93: 50–53. 4 Desai

[13] Robert Herriman, 2023, Nigeria approves R21 Malaria Vaccine. Available at https://www.nafdac.gov.ng/press-briefing-by-prof-mojisola-christianah-adeyeye-director-general-national-agency-for-food-and-drug-administration-and-control-nafdac-on-the-regulatory-approval-of-r21-malaria-vaccine-by-nafdac/

[14] National Malaria Indicator Survey (NMIS, 2015): Key indicators. National Malaria Elimination Programme, Abuja Nigeria. 2015; p96 & 99.

[15] National Population Commission (NPC, 2019). Nigeria Demographic and Health Survey 2018.Abuja, Nigeria, and Rockville, Maryland, USA: NPC and ICF.

[16] IRI Database, (2006): International Research Institute for Climate & Society (IRI), Lamont Campus, Palisades, New York: The Earth Institute at Columbia University.

[17] World Health Organization, 2021, WHO list of Prequalified in vitro diagnostic products 2021. https://extranet.who.int/pqweb/sites/default/files/documents/210309_prequalified_product_list.pdf

[18] Federal Ministry of Health, 2018, National guidelines for Diagnosis and Treatment of Malaria, 4th edition. National Malaria Elimination Programme, Abuja Nigeria Available at https://dhsprogramme.com/publication-fr359-dhs-final-reports.cfm

[19] National Bureau for Statistics, 2019, Poverty and Inequality in Nigeria: executive summary 2020. Available at https://www.nigerianstat.gov.ng

[20] Alsan, Marcella M.; Westerhaus, Michael; Herce, Michael; Nakashima, Koji; Farmer, Paul E. (2011). "Poverty, Global Health, and Infectious Disease: Lessons from Haiti and Rwanda" https://www.ncbi. nlm.nih.gov/pmc/articles/PMC3168775

[21] James Cheaveau, Daniel Castaneda Mogollon, Md Abu Naser Mohon, Lemu Golassa, Delenasaw Yewhalaw& Dylan R Pillai (2019): Asymptomatic malariain the clinical and public health context, Expert Review of Anti-infective Therapy, DOI: 10.1080/14787210.2019.1693259. available at https://doi.org/10.1080/14787210.2019.1693259

[22] Akili K. Kalinga, Reginald A. Kavishe, Deus S. Ishengma, (2019): Prevalence of asymptomatic malaria infections in selected military camps in Tanzania.Available at https://www.academia.edu/73636371/Prevalence_of_asymptomatic_malaria_infections_in_selected_military_camps_in_Tanzania

[23] Ignatius C. N., Daniel Okyere, Juliana Yartey Enos, et al., 2019, Prevalence of asymptomatic malaria parasitaemia following mass testing and treatment in Pakro sub-district of Ghana. 2019; 19:1622. DOI: https://10.1186/s12889-009-7986-4