Abstract:

Soft tissue sarcomas (STS) of the foot and ankle are uncommon neoplasms associated with a high risk of local recurrence and metastasis. These tumors are often treated with amputation, yet the impact of this approach on patient outcomes remains unclear. The purpose of this review was to assess the risks associated with (1) disease-related death, (2) local recurrence, (3) metastasis, and (4) whether the type of surgery—amputation versus limb-sparing—affects disease-related survival. Historically, sarcomas of the foot and ankle have been treated with amputation due to the challenges in managing localized disease and preserving functional foot structure. However, the potential for limb preservation may be further complicated by unanticipated surgical excisions.

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