Abstract:

Fibroadenomas are common, well-circumscribed, and typically benign breast tumors often present in young women. Although also generally benign, phyllodes tumors are less common and are characterized by stromal overgrowth leading to a “leaf-like” architecture. When these two lesions coexist, the differential diagnosis becomes more complex, as both conditions can present with overlapping symptoms and imaging findings, such as palpable masses or irregularities on mammography and ultrasound. Histologically, the distinction between fibroadenomas and phyllodes tumors relies on the degree of stromal overgrowth and atypia. This is a case report of a 38-year-old multiparous female who presented with a lump in both breasts. Following imaging and biopsy, it was proved that the patient had phyllodes tumor concurrent with multiple fibroadenomas. We proceeded with a simple mastectomy for the phyllodes tumor due to its high chance of recurrence, and excision and biopsy for the fibroadenomas. The treatment protocol differs greatly for phyllodes tumors and fibroepithelial neoplasia; hence, it is important to differentiate and confirm the diagnosis before deciding on the treatment protocol. This paper emphasizes the need for heightened awareness and a multidisciplinary approach in the management of patients with this unusual combination of breast lesions.

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