Abstract:

Aavarampoo, scientifically known as Cassia auriculata, is a flowering plant belonging to the legume family, used in Ayurvedic medicine. Studies have shown that the phytochemical constituents of Aavarampoo, including flavonoids and tannins, contribute to its ability to modulate inflammatory responses in the body. Diclofenac is a well-known nonsteroidal anti-inflammatory drug (NSAID) it works by inhibiting cyclooxygenase (COX) enzymes, which play a key role in the inflammatory process. This makes it a suitable comparator when assessing the anti-inflammatory effects of Aavarampoo, which may have a different but potentially complementary mechanism. Given its widespread use in clinical practice, comparing Aavarampoo to diclofenac can provide relevant insights into its potential as a viable alternative or adjunct therapy in treating inflammation. Materials And Methods: This study is to explore Avarampoo’s anti-inflammatory potential against Diclofenac by membrane stabilizing property (Maria dragan et al, 2016) and by protein denaturation method. Results: When assessed for membrane stabilizing activity, Aavarampoo exhibited commendable protective effects on human red blood cells (HRBC), demonstrating a maximum inhibition of 50.0% at a concentration of 500 µg. diclofenac exhibited significant inhibition of albumin denaturation, with a maximum percentage inhibition of 87.5% at 500 µg. In contrast, the Aavarampoo extract showed a progressive increase in inhibition, achieving 50.0% at the highest concentration tested. Conclusion: Aavarampoo possesses notable anti-inflammatory properties; further research could enhance our understanding of its mechanisms and broaden its applications in complementary health strategies.

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