Abstract:

This research focuses on the fabrication and characterization of chitosan/tricalcium phosphate/quercetin-doped silver membranes for guided bone regeneration (GBR). The study aims to investigate the potential benefits of these membranes in facilitating the regeneration of bone tissue in areas with bone defects or insufficient bone volume, particularly in dental and orthopaedic surgeries, as well as periodontitis. Material characterization using FTIR, XRD, and SEM was conducted to confirm the functional group, the presence of uniform fibres, and a hydrophilic surface. The study also evaluated the material's biocompatibility and its potential application in periodontitis treatment. The study demonstrated the material's hydrophilic nature, biocompatibility, as well as its potential applications in periodontitis treatment due to its compatibility with cell attachment and nourishment, anti-inflammatory properties, and bone-forming ability. The chitosan/tricalcium phosphate/quercetin-doped silver membranes show promise in guided bone regeneration and potential implications in periodontitis treatment, offering a multifunctional approach for enhancing bone tissue regeneration.

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