Serum Biochemical Parameters Harmonized with Demographic Characteristics in Bladder Cancer Patients

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DOI: 10.21522/TIJPH.2013.13.02.Art081

Authors : Mahmoud A. M. Fakhri, Ayad k. Ibrahim

Abstract:

This study investigated variations in biochemical parameters across different age groups, BMI categories, and smoking status to assess metabolic health and disease risk. Key findings include age-related trends; stable parameters: Total cholesterol (TC), HDL-C, LDL-C, atherogenic index, urea, ALT, AST, total protein (TP), and albumin showed no significant differences across age groups (under 50, 50–65, and over 65 years). Age-Dependent Changes Triglycerides (TG) and VLDL-C levels decreased significantly with age, while creatinine levels increased significantly with advancing age. BMI-Related Trends: Significant Increases TC and LDL-C levels rose significantly with higher BMI (normal weight, overweight, obese). Stable Parameters TG, HDL-C, VLDL-C, atherogenic index, urea, creatinine, ALT, and AST showed no significant differences across BMI groups. Smoking-Related Trends: Smokers exhibited trends of elevated levels in urea, creatinine, ALT, AST, TC, TG, VLDL, and LDL compared to non-smokers, though none of these differences were statistically significant. HDL was slightly lower, and total protein and albumin showed minimal differences in smokers, none of which were statistically significant. Age significantly influences TG, VLDL-C, and creatinine levels, highlighting the importance of age-specific metabolic assessments. Higher BMI is associated with adverse lipid profiles, particularly elevated TC and LDL-C, emphasizing the need for weight management in cardiovascular health. Smoking may impact biochemical parameters, but further research is required to confirm these trends. These findings underscore the importance of considering age, BMI, and lifestyle factors when evaluating metabolic health and disease risk.

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