Fabrication and Characterisation of Chitosan/ Tricalcium Phosphate/ Quercetin Doped Magnesium Membranes for Guided Bone Regeneration
Abstract:
Periodontal disease, characterized by gum inflammation, can lead to bone resorption. Chitosan, derived from chitin in marine crustaceans and fungi, is promising for bone tissue engineering due to its low toxicity. Magnesium ions, essential for bone metabolism, enhance mechanical strength and osteogenesis. This study fabricated and characterized chitosan/tricalcium phosphate/quercetin-doped magnesium membranes for guided bone regeneration. FTIR confirmed the presence of chitosan and magnesium, while SEM images showed increased fibre diameter. A water contact angle of 69° and a slight increase in matrix mineralization indicate the material’s hydrophilicity and biocompatibility, making it a potential treatment for periodontitis. The results emphasize the dual potential of these membranes in bone healing and improved patient outcomes, offering novel approaches for regenerative medicine.References:
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