Abstract:

A number of infectious diseases remain neglected, such as the sleeping sickness and often occur in individuals who are additionally affected by HIV/AIDS and malaria, making the problem even more serious. In this article we will be discussing the clinical interactions between HIV/AIDS, malaria and trypanosomiasis infection.

The discussed patient is a 34 year old female who presented with an intermittent fever lasting approximately three months and behavioural problems persisting for one week. The patient reported unprotected sex with multiple sexual partners. She was diagnosed with HIV (WHO stage III), human African trypanosomiasis stage II and malaria with high parasitemia. The patient receives treatment for malaria and trypanosomasis but died of neurological causes.

Discussion: There is a scarcity of data regarding the coexistence of HIV/AIDS, trypanosomasis, and malaria in a specific patient. This creates a complicated situation for diagnosis and treatment.

Conclusion: Co-infections through various infectious agents are common in sub-Saharan African creating important diagnostic, therapeutic, and prognostic implications.

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