Knowledge, Attitude and Acceptability of Premarital Genetic Services for Sickle Cell Disease among Undergraduates of a Nigerian Private Tertiary Institution
Nigeria annually, 150,000 children are born with sickle cell anemia. One way of
preventing sickle cell disease is through premarital genetic counseling and
screening. This study therefore assessed the knowledge, attitude and
acceptability of premarital genetic services for sickle cell disease among
Babcock University Undergraduates.
study was descriptive and cross sectional in design. Three hundred and seventy
seven respondents were randomly selected using multistage sampling technique.
Data was collected using a validated semi-structured questionnaire that was
self-administered with a Cronbach-Alpha test of 0.747. It was analyzed using
the statistical package for social science (SPSS) version 21 to generate
descriptive and inferential statistics.
results showed that more than half 229 (60.7%) of the respondents were females
while 148 (39.3%) of the respondents were males. Three hundred and fifteen of
the respondents were between the age range of 16-20 years with the mean age of
18.99 and SD±0.107. 363 (96.3%) of respondents had heard of sickle cell
diseasewhile, 229 (60.7%) agreed that intending couples should attend
premarital genetic services and thus showed positive attitude. Another 350
(92.8%) of the respondents would undergo premarital genetic services if it is
available. There is a significant difference between knowledge and acceptability
of respondents towards premarital genetic services (P= 0.047)
conclusion, the respondents had a high level of knowledge and acceptability on
premarital genetic services and sickle cell disease. All sectors should
increase efforts in creating awareness about premarital genetic services and
Premarital, genetic services, Knowledge, Acceptability, Attitude, sickle cell
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