Isoniazid Preventive Therapy Implementation among People Living with HIV/AIDS Enrolled in Care at Specialist Hospital Yola, Nigeria
Background: Nigeria ranks 5th among the 22 countries that contributed 80%
of the global Tuberculosis (TB) burden. The risk of developing TB is between 20
and 37 times greater in people living with HIV (PLWHIV) than among those who do
not have HIV infection. The purpose of this study was to assess the level of Isoniazid
Preventive Therapy (IPT) implementation among PLWHIV.
Methods: Retrospective cohort study conducted to examine the IPT implementation among
the PLWHIV in Specialist Hospital Yola, Nigeria. Information’s were extracted from
the IPT enrolment register and client’s folders, analyzed with excel and compared
with the data in the District Health Information System (DHIS). Chi-square test
was used to measure the strength of associations between the various variables and
probability of statistical significant level set < 0.05 at 95% Confidence interval
Results: Eight hundred and seventy-three (873) clients were enrolled in to HIV care
and treatment from January-December 2015 and were all screened for TB. 777 (89%)
clients had no presumptive TB, only 273 (35%) clients were initiated on IPT out
of those without presumptive TB. 143 (93%) clients on ART completed their IPT as
against the 97 (80%) Pre-ART clients that completed IPT.
Conclusion: The IPT utilization in the prevention of TB among the PLWHIV in this health
facility was very low, however consistent availability of Isoniazid and effective
adherence counselling to eligible PLWHIV before commencement of IPT would help in
increasing uptake and reducing the rate of defaulters on IPT.
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