changed its malaria treatment drug (AMD) policy in 2005 from use of chloroquine
(CQ) and sulphadoxine-pyrimethamine (SP) to more effective Artemisinin-based
combination therapy (ACT). SP is exclusively reserved for malaria in pregnancy prevention.
Sixty percent of Nigerians patronize Patent Medicine Vendors (PMVs). This study
assessed AMDs stocking and dispensing practices of urban and rural based PMVs. This
is a cross-sectional survey of 120 PMVs in ten LGAs of Akwa Ibom State,
Nigeria. The LGAs were divided into five urban and five rural.12 PMVs were
selected from each LGA. A one page questionnaire was used to elicit information
on brand-names of AMDs, drug-active-ingredients, cost, and popularity amongst
clients. Data was analyzed and results presented in simple frequencies, mean,
and confidence intervals (CI). 1,150 AMDs were found under 86 brand-names. Mean
in urban shops was 22.6 [SD±20.5] compared to rural 20.1 [SD±16.9]. ACT was
more common in urban (71.1% at 95% CI: 0.579-0.822); SP (36.4% at 95%
0.109-0.692); CQ (33.3% at 95% CI: 0.075-0.701); and rural ACT (28.8 % at 95%
CI: 0.178-0.421); SP (63.6% at 95% CI: 0.308-0.891); CQ (66.7%. at 95% CI: 0.299-0.925). Drug popularity in both areas, clients
preferred ACT (74.0%, CI: 0.639-0.832); CQ (12.7%, CI: 0.066-0.217), SP (8.6%,
CI: 0.033-0.161); and MADs (4.8%, 0.013-0.115).The cost of drugs ranged <
N100 per dose for SP and CQ to ACTs > N301. Twelve years after the change, non-recommended
drugs are still prescribed. Promoting training, cost reduction and availability
of appropriate and efficacious AMDs may boost current malaria control efforts.
Antimalarial drugs, patent medicine vendors, urban and rural, stocking and
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