Evaluation of Prevention of Mother-To-Child Transmission of HIV Services in Selected Health Facilities in Lagos State, Nigeria

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DOI: 10.21522/TIJPH.2013.08.02.Art039

Authors : Ajayi, Idowu Funmilola, Owopetu Christian Adetoun, Ademuyiwa, Iyabo Yewande

Abstract:

Introduction: Prevention of Mother-to-Child transmission (PMTCT) of HIV is a global response to reduce the risk of mother-to-child transmission of HIV which can occur in-utero, during childbirth or during breastfeeding, specific services rendered to HIV positive pregnant women are crucial in preventing vertical transmission, therefore, this study evaluated Prevention of Mother-To-Child Transmission of HIV services in selected health facilities in Lagos State, Nigeria.

Method: The study adopted a descriptive survey design. The sample size was 19 health facilities in Lagos state, a multi stage sampling procedure was used to select the samples. Two instruments were used for data collection, observational checklist and past records of PMTCT activities of the participating facilities from January 2017 to December 2019. The checklist was pre tested with a reliability coefficient of 0.96. Analysis of data was done using descriptive statistics and inferential statistics.

Results: The findings show that in all the selected health facilities 92.8% of the structures in terms of equipment/supplies were available and functional. majority of the health care providers listed were available, there was availability of recommended PMTCT services in all selected health facilities, it was also revealed that there was a positive significant relationship between the available structure and PMTCT services (r =.347; p = 0.0146 < .05).

Conclusion: The availability of PMTCT structures, resources, equipment/supplies and service providers have significant influence on prevention of mother to child transmission of HIV services provision. Also, PMTCT services have influence on the final outcomes of exposed infants.

References:

[1].   Adeleke, S., Mukhtar-Yola, M., Gwarzo, D., & Ladan, Z.F. (2009). Premilinary investigation of adherence to antiretroviral therapy among children in Aminu Kano Teaching hospital, Nigeria African journal of AIDS Research, 5 (2), 141-144.

[2].   Agboghoroma, C.O., Sagay, S.A., & Ikechebelu, J.I (2013). Nigeria prevention of mother to child transmission of human Immunu deficiency Virus. Journal of HIV and Human Reproduction. Retrieved from www.j-hhr.org

[3].   Ammann, A., Hemandez, W., Goyanes, M., Miguez, M.J., & Shor-Posner, G. (2017). Prevention of Mother-to-Child Transmission (PMTCT) of HIV. Retrieved from https://doi.org/BMJ, 329 (7475), 1147-1150.

[4].   Avert, (2019). Global information and education on HIV and AIDS. Retrieved from www.avert.org.

[5].   Bokharaei, S.F, Jarchi, M., Esghaei, M., Kiani, S.J (2018). The frequency of HIV -1 Infection in Iranian children and determination of the Transmitted Drug Resistance in treatment –naïve children. Current HIV Research journal retrieved from http://doi.10.2174/1570162x17666191106111211

[6].   Chukwuemeka, I.K., Fatima, M.I., Ovavi, Z.K., & Olukayode, O., (2014). The impact of HIV prevention of mother to child transmission program in a Nigerian early infant diagnosis centre. Niger Med J, 1 (3), 204–8.

[7].   Cleary, Paul D., & O'kane, & Margaret E. (2014). Evaluating the Quality of Health care: Comparati effectiveness of congregation versus clinic-based approach to prevention of mother-to-child HIV-transmission: Study protocol for a cluster randomized controlled trial. Retrieved from

http://www.esourceresearch.org/tabid/794/default.aspx.

[8].   Dabis, F. (2014). Prevention of mother to child Transmission of HIV: Evaluation Centre. Evaluation of a Pilot Programme in a District Hospital in rural Zimbabwe. Retrieved from

www.wmich.edu/evalctr/checklists/cippchecklist.htm.

[9].   Fasawe O, Avila C, Shaffer N, Schouten E, & Chimbwandira Fl. (2013). Cost-effectiveness analysis of Option B+ for HIV prevention and treatment of mothers and children in Malawi. Retrieved from http://www.pubmedcentral.nih.gov/articlerender.fcgi.

[10].  Federal Government of Nigeria, (2010). National Guidelines on Prevention of Mother to Child Transmission (PMTCT) of HIV in Nigeria. 4th Ed. Abuja.

[11].  Federal Ministry of Health (2009). Technical Report 2008 National HIV sero-prevalence sentinel survey among women attending antenatal clinics in Nigeria. National AIDS/STI Control Programme (NASCP). Abuja.

[12].  Federal Ministry of Health, (2008). Technical Report 2008 National HIV sero-prevalence sentinel survey among women attending antenatal clinics in Nigeria. National AIDS/STI Control Programme (NASCP). Abuja.

[13].  Ferguson, W., Goode, M., Walsh, A., Gavin, P., & Butler, K. (2011). “Evaluation of 4 weeks' neonatal antiretroviral prophylaxis as a component of a prevention of mother-to-child transmission program in a resource-rich setting,” Pediatric Infectious Disease Journal, 3 (5), 408–412.

[14].  Hill, A., Dauncey, T., Levi, J., Heath, K., & Pérez, C. (2015). Higher risks of mother-to-child HIV transmission in countries with lower HIV prevalence: UNAIDS 2013 results for 32 countries with generalised epidemics. Journal of Virus Eradication. Retrieved from https://doi.org/PMid: 2748242 PMCid: PMC4 946657.

[15].  Horwood, C., Haskins, L., Vermaak, K., Phakathi, S., Subbaye, R., & Doherty, T. (2015). Prevention of Mother to Child Transmission of HIV (PMTCT) programme in KwaZulu-Natal, South Africa: an evaluation of PMTCT implementation and integration into routine maternal, child and women’s health services. Trop Med Int Health, 15 (9), 992–9.

[16].  Iregbu, C.I., Fatimo, I., Kabiru, Z.K., & Olukayode, O. (2014). The impact of a HIV prevention of mother to child transmission program in a Nigerian early infant diagnosis centre. Niger Med Journal, 55 (3), 204-208.

[17].  Marilyn, K., Simon, & Jim G. (2013). Dissertation and scholarly research: Expost facto research; Recipes for success. Retrieved from www.dissertationrecipes.com.

[18].  Mateus R, Bolzan A, Gomes P, Brito J, Carvalho AP, & Cardoso Y. (2014). Cost-effectiveness of early infant HIV diagnosis of HIV-exposed infants and immediate antiretroviral therapy in HIV-infected children under 24 months in Thailand. Journal medi, 9 (3), 914.

[19].  Myer, L., Phillips, T., Zerbe, A., (2018). Integration of postnatal services improves MCH and ART National Agency for the Control of AIDS. Retrieved from

http://dx.doi.org/ 10.1371/journal.pmed.1002547.

[20].  NACA, (2011). Fight AIDS to finish: update on HIV/AIDS epidemic and response in Nigeria. Retrieved from http://naca.gov.ng/content/view/423/lang.en/#epidemiology.

[21].  Neubert, J., Pfeffer, M., & Borkhard, A. (2013). “Risk adapted transmission prophylaxis to prevent vertical HIV-1 transmission: effectiveness and safety of an abbreviated regimen of postnatal oral Zidovudine,” BMC Pregnancy and Childbirth, 13 (22), RF https://doi.org/

[22].  Nielsen-Saines, K., Watts, D.H., & Veloso, V.G. (2012). “Three postpartum antiretroviral regimens to prevent intrapartum HIV infection,” The New England Journal of Medicine, 366 (25), 2368–2379.

[23].  Perez, F., Orne-Gliemann, J., Mukotakwa, T., Miller, A., Glenshaw, M., Mahomva, A., Perez, T., Peňa, R.R.N., Tavarez-Rojas, M., Peňa, C., Quiňonez, S., Buttler, M., Ammann, A., Hemandez, W., Goyanes, M., Miguez, M.J., & Shor-Posner, G. (2014). Preventing Mother –to-Child HIV Transmission in a Developing Country: The Dominican Republic Experience. JAIDS, 34 (5), 506-511.

[24].  Polit, D.F., & Beck. C. T. (2017). Nursing Research: Generation and Assessing Evidence for Nursing practice (10th ed) Wolters Kluwer, Philadelphia programmes with other health services for preventing HIV infection and improving HIV outcomes in developing countries. Retrieved from https://www.ncbi.nim.gov/pubmed/21678382.

[25].  Radin, A. K., Abutu, A. A., Okwero, M. A., Adler, M. R., Anyaike, C., & Asiimwe, H. T., (2017). Confronting challenges in monitoring and evaluation: Innovation in the context of the global plan towards the elimination of new HIV infections among children by 2015 and keeping their mothers alive. Journal of Acquired Immune Deficiency Syndromes, 75 (1), 66–75.

[26].  Redmond, A.M., & McNamara, J.F., (2015). The road to eliminate mother –to- child HIV transmission. Journal pediatr (Rio J) 91 (6), 509-511.

[27].  UNAIDS, (2016). United States Presidents Emergency Plan for AIDS Relief (PEPFAR), Unite Nations Children's Fund (UNICEF), On the Fast-Track to an AIDS-Free Generation: The Incredible Journey of the Global Plan Towards the Elimination of New HIV Infections Among Children by 2015 and Keeping Their Mothers Alive. Geneva, Switzerland.

[28].  UNAIDS, (2015). Global Plan Progress Report: Towards the Elimination of New HIV Infections Among Children and Keeping Their Mothers Alive. Geneva, Switzerland.

[29].  Warren, Charlotte E., Abuya, Timothy, Kanya, Lucy, Obare, Francis, Njuki, Rebecca, Temmerman, Marleen and Bellows, Ben (2015) A cross sectional comparison of postnatal care quality in facilities participating in a maternal health voucher program versus non-voucher facilities in Kenya. BMC Pregnancy and Childbirth, 15 (1). 1471-2393.

[30].  Wiegert, K., Dinh, T.H., Mushavi, A, (2014). Integration of prevention of mother-to-child transmission of HIV (PMTCT) postpartum services with other HIV care and treatment services within the maternal and child health setting in Zimbabwe, Retrieved from https://www.ncbi.nih.gov/pubmed

[31].  World Health Organization, (2019). Global Health Observatory (GHO) data, Retrieved from https://www.who.int/gho/hiv/epidemic_response/PMTCT_text/en/

[32].  World Health Organization, (2015). Guideline on when to start antiretroviral therapy and on pre-exposure prophylaxis for HIV'. Retrieved from https://apps.who.int/irrs/bitstream

[33].  World Health Organization (2016) United Nations Children's Fund (UNICEF), Elizabeth Glaser Pediatric AIDS Foundation. The Double Dividend: A Synthesis of Evidence for Action to Improve Survival of HIV “Exposed” Children in the Era of EMTCT and Renewed Child Survival Campaigns. New York. Retrieved from

http://www.childrenandaids.org/css/Synthesis

[34].  World Health Organization. (2016) Consolidated Guidelines on the use of Antiretroviral Drugs for Treating and Preventing HIV Infection: Recommendations for a Public Health Approach. Geneva: World Health Organization. Retrieved from http://apps.who.int/iris/bitstream.

[35].  World Health Organization, (2016). Mother-to-child transmission of HIV; 2016. Technical Consultation on the Integration of HIV Interventions into Maternal, New-born, and Child Health Services. Report of a WHO Meeting, Geneva, Switzerland, Retrieved from http://apps.who.int/iris/bitstream.

[36].  World Health Organization, (2010). Antiretroviral drugs for treating pregnant women and preventing HIV infection in infants. Retrieved from http://apps.who.int/iris/bitstream.