Abstract:

The discovery of stem cells in dental pulp has expanded our understanding concerning the various mechanisms that play a substantial role in the maintenance of dental pulp homeostasis to improve health and also regarding the pulp response to injury. Stems cells play a pivotal role in the physiology of the dental pulp tissue throughout the entire lifespan of the tooth. The ideology that these cells are intimately associated with regulating pulp angiogenesis as a response to cariogenic challenges is also inferred. In recent times, we are witnessing an increasing number of passionate individuals showing enthusiasm in the field of regenerative endodontics as stem cells exhibit potential benefits in dental pulp tissue engineering. The article here focuses predominantly on stem cells—the dental stem cells and non-dental stem cells which play an active part in benefitting pulpal necrosis tooth, the cardinal objective of these cells in the field of endodontic therapy, and the current, as well as the future role, stem cells could play in the clinical practice of endodontics eventually.

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